Sfoglia per Autore
Dual PI3K/mTOR inhibitor, XL765 (SAR245409), shows superior effects to sole PI3K [XL147 (SAR245408)] or mTOR [rapamycin] inhibition in prostate cancer cell models
2016-01-01 Gravina, GIOVANNI LUCA; Mancini, Andrea; Scarsella, Luca; Colapietro, Alessandro; Jitariuc, Ana; Vitale, Flora; Marampon, Francesco; Ricevuto, Enrico; Festuccia, Claudio
C-Myc Sustains Transformed Phenotype and Promotes Radioresistance of Embryonal Rhabdomyosarcoma Cell Lines
2016-01-01 Gravina, GIOVANNI LUCA; Festuccia, Claudio; Popov, V. M.; Di Rocco, A.; Colapietro, Alessandro; Sanita', Patrizia; DELLE MONACHE, Simona; Musio, D.; De Felice, F.; DI CESARE, Ernesto; Tombolini, V.; Marampon, F.
Increased expression and activity of p75NTR are crucial events in azacitidine-induced cell death in prostate cancer
2016-01-01 Gravina, GIOVANNI LUCA; Marampon, Francesco; Sanita', Patrizia; Mancini, Andrea; Colapietro, Alessandro; Scarsella, Luca; Jitariuc, Ana; Biordi, ASSUNTA LEDA; Ficorella, Corrado; Festuccia, Claudio
Cyclin D1 silencing suppresses tumorigenicity, impairs DNA double strand break repair and thus radiosensitizes androgenindependent prostate cancer cells to DNA damage
2016-01-01 Marampon, Francesco; Gravina, GIOVANNI LUCA; Ju, X; Vetuschi, Antonella; Sferra, Roberta; Casimiro, M. C; Pompili, Simona; Festuccia, Claudio; Colapietro, Alessandro; Gaudio, E; DI CESARE, Ernesto; Tombolini, V; Pestell, R. G.
The brain-penetrating CXCR4 antagonist, PRX177561, increases the antitumor effects of bevacizumab and sunitinib in preclinical models of human glioblastoma
2017-01-01 Gravina, GIOVANNI LUCA; Mancini, Andrea; Marampon, Francesco; Colapietro, Alessandro; DELLE MONACHE, Simona; Sferra, Roberta; Vitale, Flora; Richardson, Peter J.; Patient, Lee; Burbidge, Stephen; Festuccia, Claudio
UniPR1331, a small molecule targeting Eph/ephrin interaction, prolongs survival in glioblastoma and potentiates the effect of antiangiogenic therapy in mice
2018-01-01 Festuccia, Claudio; Gravina, Giovanni Luca; Giorgio, Carmine; Mancini, Andrea; Pellegrini, Cristina; Colapietro, Alessandro; Monache, Simona Delle; Maturo, Maria Giovanna; Sferra, Roberta; Chiodelli, Paola; Rusnati, Marco; Cantoni, Annamaria; Castelli, Riccardo; Vacondio, Federica; Lodola, Alessio; Tognolini, Massimiliano
Efficient optimization of pyrazolo[3,4-d]pyrimidines derivatives as c-Src kinase inhibitors in neuroblastoma treatment
2018-01-01 Molinari, Alessio; Fallacara, Anna Lucia; Di Maria, Salvatore; Zamperini, Claudio; Poggialini, Federica; Musumeci, Francesca; Schenone, Silvia; Angelucci, Adriano; Colapietro, Alessandro; Crespan, Emmanuele; Kissova, Miroslava; Maga, Giovanni; Botta, Maurizio
Dual PI3 K/mTOR inhibition reduces prostate cancer bone engraftment altering tumor-induced bone remodeling
2018-01-01 Mancini, A.; Colapietro, A.; Pompili, S.; Del Fattore, A.; Delle Monache, S.; Biordi, L. A.; Angelucci, A.; Mattei, V.; Liang, C.; Gravina, G. L.; Festuccia, C.
Immunolocalization of Advanced Glycation End Products, Mitogen Activated Protein Kinases, and Transforming Growth Factor-β/Smads in Pelvic Organ Prolapse
2018-01-01 Vetuschi, Antonella; Pompili, Simona; Gallone, Anna; D'Alfonso, Angela; Carbone, MARIA GABRIELLA; Carta, Gaspare; Festuccia, Claudio; Gaudio, Eugenio; Colapietro, Alessandro; Sferra, Roberta
Correction: The first-in-class alkylating deacetylase inhibitor molecule tinostamustine shows antitumor effects and is synergistic with radiotherapy in preclinical models of glioblastoma (Journal of Hematology and Oncology (2018) 11(32) DOI: 10.1186/s13045-018-0576-6)
2018-01-01 Festuccia, C; Mancini, A; Colapietro, A; Gravina, G L; Vitale, F; Marampon, F; Delle Monache, S; Pompili, S; Cristiano, L; Vetuschi, A; Tombolini, V; Chen, Y; Mehrling, T
Expression of Peroxisome Proliferator-Activated Receptor Alpha (PPARα) in Non-Somatotroph Pituitary Tumours and the Effects of PPARα Agonists on MMQ Cells
2018-01-01 Polidoro, Michela Anna; Rotondi, Sandra; Morace, Roberta; Rostomyan, Liliya; Colapietro, Alessandro; Arcella, Antonietta; Cinque, LUCA VENTURA; Angelucci, Adriano; Giangaspero, Felice; Esposito, Vincenzo; Beckers, Albert; Jaffrain-Rea, Marie-Lise
The first-in-class alkylating deacetylase inhibitor molecule tinostamustine shows antitumor effects and is synergistic with radiotherapy in preclinical models of glioblastoma
2018-01-01 Festuccia, Claudio; Mancini, Andrea; Colapietro, Alessandro; Gravina, Giovanni Luca; Vitale, Flora; Marampon, Francesco; Delle Monache, Simona; Pompili, Simona; Cristiano, Loredana; Vetuschi, Antonella; Tombolini, Vincenzo; Chen, Yi; Mehrling, Thomas
Dual CXCR4 and E-Selectin Inhibitor, GMI-1359, Shows Anti-Bone Metastatic Effects and Synergizes with Docetaxel in Prostate Cancer Cell Intraosseous Growth
2019-01-01 Festuccia, Claudio; Mancini, Andrea; Gravina, Giovanni Luca; Colapietro, Alessandro; Vetuschi, Antonella; Pompili, Simona; Ventura, Luca; Delle Monache, Simona; Iorio, Roberto; Del Fattore, Andrea; Fogler, William; Magnani, John
The brain penetrating and dual TORC1/TORC2 inhibitor, RES529, elicits anti-glioma activity and enhances the therapeutic effects of anti-angiogenetic compounds in preclinical murine models
2019-01-01 Gravina, Giovanni Luca; Mancini, Andrea; Colapietro, Alessandro; Delle Monache, Simona; Sferra, Roberta; Pompili, Simona; Vitale, Flora; Martellucci, Stefano; Marampon, Francesco; Mattei, Vincenzo; Biordi, Leda; Sherris, David; Festuccia, Claudio
The Small Molecule Ephrin Receptor Inhibitor, GLPG1790, Reduces Renewal Capabilities of Cancer Stem Cells, Showing Anti-Tumour Efficacy on Preclinical Glioblastoma Models
2019-01-01 Gravina, Giovanni Luca; Mancini, Andrea; Colapietro, Alessandro; Delle Monache, Simona; Sferra, Roberta; Vitale, Flora; Cristiano, Loredana; Martellucci, Stefano; Marampon, Francesco; Mattei, Vincenzo; Beirinckx, Filip; Pujuguet, Philippe; Saniere, Laurent; Lorenzon, Giocondo; van der Aar, Ellen; Festuccia, Claudio
Can the AGE/RAGE/ERK signalling pathway and the epithelial-to-mesenchymal transition interact in the pathogenesis of chronic rhinosinusitis with nasal polyps?
2020-01-01 Vetuschi, A; Pompili, S; Di Marco, Gp; Calvaruso, F; Iacomino, E; Angelosante, L; Festuccia, C; Colapietro, A; Sferra, R.
Crocetin and crocin from saffron in cancer chemotherapy and chemoprevention
2020-01-01 Festuccia, Claudio; Colapietro, Alessandro; Mancini, Andrea; D'Alessandro, Annamaria
Crocetin extracted from saffron shows antitumor effects in models of human glioblastoma
2020-01-01 Colapietro, A.; Mancini, A.; Vitale, F.; Martellucci, S.; Angelucci, A.; Llorens, S.; Mattei, V.; Gravina, G. L.; Alonso, G. L.; Festuccia, C.
Antitumorigenic Effects of Inhibiting Ephrin Receptor Kinase Signaling by GLPG1790 against Colorectal Cancer Cell Lines in Vitro and in Vivo
2020-01-01 Colapietro, A.; Gravina, G. L.; Petragnano, F.; Fasciani, I.; Scicchitano, B. M.; Beirinckx, F.; Pujuguet, P.; Saniere, L.; Van Der Aar, E.; Musio, D.; De Felice, F.; Mattei, V.; Martellucci, S.; Maggio, R.; Tombolini, V.; Festuccia, C.; Marampon, F.
The Botanical Drug PBI-05204, a Supercritical CO2 Extract of Nerium Oleander, Inhibits Growth of Human Glioblastoma, Reduces Akt/mTOR Activities, and Modulates GSC Cell-Renewal Properties
2020-01-01 Colapietro, A.; Yang, P.; Rossetti, A.; Mancini, A.; Vitale, F.; Martellucci, S.; Conway, T. L.; Chakraborty, S.; Marampon, F.; Mattei, V.; Gravina, G. L.; Biordi, A. L.; Wei, D.; Newman, R. A.; Festuccia, C.
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| Dual PI3K/mTOR inhibitor, XL765 (SAR245409), shows superior effects to sole PI3K [XL147 (SAR245408)] or mTOR [rapamycin] inhibition in prostate cancer cell models | 1-gen-2016 | Gravina, GIOVANNI LUCA; Mancini, Andrea; Scarsella, Luca; Colapietro, Alessandro; Jitariuc, Ana; Vitale, Flora; Marampon, Francesco; Ricevuto, Enrico; Festuccia, Claudio | |
| C-Myc Sustains Transformed Phenotype and Promotes Radioresistance of Embryonal Rhabdomyosarcoma Cell Lines | 1-gen-2016 | Gravina, GIOVANNI LUCA; Festuccia, Claudio; Popov, V. M.; Di Rocco, A.; Colapietro, Alessandro; Sanita', Patrizia; DELLE MONACHE, Simona; Musio, D.; De Felice, F.; DI CESARE, Ernesto; Tombolini, V.; Marampon, F. | |
| Increased expression and activity of p75NTR are crucial events in azacitidine-induced cell death in prostate cancer | 1-gen-2016 | Gravina, GIOVANNI LUCA; Marampon, Francesco; Sanita', Patrizia; Mancini, Andrea; Colapietro, Alessandro; Scarsella, Luca; Jitariuc, Ana; Biordi, ASSUNTA LEDA; Ficorella, Corrado; Festuccia, Claudio | |
| Cyclin D1 silencing suppresses tumorigenicity, impairs DNA double strand break repair and thus radiosensitizes androgenindependent prostate cancer cells to DNA damage | 1-gen-2016 | Marampon, Francesco; Gravina, GIOVANNI LUCA; Ju, X; Vetuschi, Antonella; Sferra, Roberta; Casimiro, M. C; Pompili, Simona; Festuccia, Claudio; Colapietro, Alessandro; Gaudio, E; DI CESARE, Ernesto; Tombolini, V; Pestell, R. G. | |
| The brain-penetrating CXCR4 antagonist, PRX177561, increases the antitumor effects of bevacizumab and sunitinib in preclinical models of human glioblastoma | 1-gen-2017 | Gravina, GIOVANNI LUCA; Mancini, Andrea; Marampon, Francesco; Colapietro, Alessandro; DELLE MONACHE, Simona; Sferra, Roberta; Vitale, Flora; Richardson, Peter J.; Patient, Lee; Burbidge, Stephen; Festuccia, Claudio | |
| UniPR1331, a small molecule targeting Eph/ephrin interaction, prolongs survival in glioblastoma and potentiates the effect of antiangiogenic therapy in mice | 1-gen-2018 | Festuccia, Claudio; Gravina, Giovanni Luca; Giorgio, Carmine; Mancini, Andrea; Pellegrini, Cristina; Colapietro, Alessandro; Monache, Simona Delle; Maturo, Maria Giovanna; Sferra, Roberta; Chiodelli, Paola; Rusnati, Marco; Cantoni, Annamaria; Castelli, Riccardo; Vacondio, Federica; Lodola, Alessio; Tognolini, Massimiliano | |
| Efficient optimization of pyrazolo[3,4-d]pyrimidines derivatives as c-Src kinase inhibitors in neuroblastoma treatment | 1-gen-2018 | Molinari, Alessio; Fallacara, Anna Lucia; Di Maria, Salvatore; Zamperini, Claudio; Poggialini, Federica; Musumeci, Francesca; Schenone, Silvia; Angelucci, Adriano; Colapietro, Alessandro; Crespan, Emmanuele; Kissova, Miroslava; Maga, Giovanni; Botta, Maurizio | |
| Dual PI3 K/mTOR inhibition reduces prostate cancer bone engraftment altering tumor-induced bone remodeling | 1-gen-2018 | Mancini, A.; Colapietro, A.; Pompili, S.; Del Fattore, A.; Delle Monache, S.; Biordi, L. A.; Angelucci, A.; Mattei, V.; Liang, C.; Gravina, G. L.; Festuccia, C. | |
| Immunolocalization of Advanced Glycation End Products, Mitogen Activated Protein Kinases, and Transforming Growth Factor-β/Smads in Pelvic Organ Prolapse | 1-gen-2018 | Vetuschi, Antonella; Pompili, Simona; Gallone, Anna; D'Alfonso, Angela; Carbone, MARIA GABRIELLA; Carta, Gaspare; Festuccia, Claudio; Gaudio, Eugenio; Colapietro, Alessandro; Sferra, Roberta | |
| Correction: The first-in-class alkylating deacetylase inhibitor molecule tinostamustine shows antitumor effects and is synergistic with radiotherapy in preclinical models of glioblastoma (Journal of Hematology and Oncology (2018) 11(32) DOI: 10.1186/s13045-018-0576-6) | 1-gen-2018 | Festuccia, C; Mancini, A; Colapietro, A; Gravina, G L; Vitale, F; Marampon, F; Delle Monache, S; Pompili, S; Cristiano, L; Vetuschi, A; Tombolini, V; Chen, Y; Mehrling, T | |
| Expression of Peroxisome Proliferator-Activated Receptor Alpha (PPARα) in Non-Somatotroph Pituitary Tumours and the Effects of PPARα Agonists on MMQ Cells | 1-gen-2018 | Polidoro, Michela Anna; Rotondi, Sandra; Morace, Roberta; Rostomyan, Liliya; Colapietro, Alessandro; Arcella, Antonietta; Cinque, LUCA VENTURA; Angelucci, Adriano; Giangaspero, Felice; Esposito, Vincenzo; Beckers, Albert; Jaffrain-Rea, Marie-Lise | |
| The first-in-class alkylating deacetylase inhibitor molecule tinostamustine shows antitumor effects and is synergistic with radiotherapy in preclinical models of glioblastoma | 1-gen-2018 | Festuccia, Claudio; Mancini, Andrea; Colapietro, Alessandro; Gravina, Giovanni Luca; Vitale, Flora; Marampon, Francesco; Delle Monache, Simona; Pompili, Simona; Cristiano, Loredana; Vetuschi, Antonella; Tombolini, Vincenzo; Chen, Yi; Mehrling, Thomas | |
| Dual CXCR4 and E-Selectin Inhibitor, GMI-1359, Shows Anti-Bone Metastatic Effects and Synergizes with Docetaxel in Prostate Cancer Cell Intraosseous Growth | 1-gen-2019 | Festuccia, Claudio; Mancini, Andrea; Gravina, Giovanni Luca; Colapietro, Alessandro; Vetuschi, Antonella; Pompili, Simona; Ventura, Luca; Delle Monache, Simona; Iorio, Roberto; Del Fattore, Andrea; Fogler, William; Magnani, John | |
| The brain penetrating and dual TORC1/TORC2 inhibitor, RES529, elicits anti-glioma activity and enhances the therapeutic effects of anti-angiogenetic compounds in preclinical murine models | 1-gen-2019 | Gravina, Giovanni Luca; Mancini, Andrea; Colapietro, Alessandro; Delle Monache, Simona; Sferra, Roberta; Pompili, Simona; Vitale, Flora; Martellucci, Stefano; Marampon, Francesco; Mattei, Vincenzo; Biordi, Leda; Sherris, David; Festuccia, Claudio | |
| The Small Molecule Ephrin Receptor Inhibitor, GLPG1790, Reduces Renewal Capabilities of Cancer Stem Cells, Showing Anti-Tumour Efficacy on Preclinical Glioblastoma Models | 1-gen-2019 | Gravina, Giovanni Luca; Mancini, Andrea; Colapietro, Alessandro; Delle Monache, Simona; Sferra, Roberta; Vitale, Flora; Cristiano, Loredana; Martellucci, Stefano; Marampon, Francesco; Mattei, Vincenzo; Beirinckx, Filip; Pujuguet, Philippe; Saniere, Laurent; Lorenzon, Giocondo; van der Aar, Ellen; Festuccia, Claudio | |
| Can the AGE/RAGE/ERK signalling pathway and the epithelial-to-mesenchymal transition interact in the pathogenesis of chronic rhinosinusitis with nasal polyps? | 1-gen-2020 | Vetuschi, A; Pompili, S; Di Marco, Gp; Calvaruso, F; Iacomino, E; Angelosante, L; Festuccia, C; Colapietro, A; Sferra, R. | |
| Crocetin and crocin from saffron in cancer chemotherapy and chemoprevention | 1-gen-2020 | Festuccia, Claudio; Colapietro, Alessandro; Mancini, Andrea; D'Alessandro, Annamaria | |
| Crocetin extracted from saffron shows antitumor effects in models of human glioblastoma | 1-gen-2020 | Colapietro, A.; Mancini, A.; Vitale, F.; Martellucci, S.; Angelucci, A.; Llorens, S.; Mattei, V.; Gravina, G. L.; Alonso, G. L.; Festuccia, C. | |
| Antitumorigenic Effects of Inhibiting Ephrin Receptor Kinase Signaling by GLPG1790 against Colorectal Cancer Cell Lines in Vitro and in Vivo | 1-gen-2020 | Colapietro, A.; Gravina, G. L.; Petragnano, F.; Fasciani, I.; Scicchitano, B. M.; Beirinckx, F.; Pujuguet, P.; Saniere, L.; Van Der Aar, E.; Musio, D.; De Felice, F.; Mattei, V.; Martellucci, S.; Maggio, R.; Tombolini, V.; Festuccia, C.; Marampon, F. | |
| The Botanical Drug PBI-05204, a Supercritical CO2 Extract of Nerium Oleander, Inhibits Growth of Human Glioblastoma, Reduces Akt/mTOR Activities, and Modulates GSC Cell-Renewal Properties | 1-gen-2020 | Colapietro, A.; Yang, P.; Rossetti, A.; Mancini, A.; Vitale, F.; Martellucci, S.; Conway, T. L.; Chakraborty, S.; Marampon, F.; Mattei, V.; Gravina, G. L.; Biordi, A. L.; Wei, D.; Newman, R. A.; Festuccia, C. |
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