BIORDI, ASSUNTA LEDA

BIORDI, ASSUNTA LEDA  

Dipartimento di Scienze cliniche applicate e biotecnologiche  

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Multiple Antitumor Molecular Mechanisms Are Activated by a Fully Synthetic and Stabilized Pharmaceutical Product Delivering the Active Compound Sulforaphane (SFX-01) in Preclinical Model of Human Glioblastoma 1-gen-2021 Colapietro, Alessandro; Rossetti, Alessandra; Mancini, Andra; Martellucci, Stefano; Ocone, Giuseppe; Pulcini, Fanny; Biordi, Leda; Cristiano, Loredana; Mattei, Vincenzo; Delle Monache, Simona; Marampon, Francesco; Gravina, Giovanni Luca; Festuccia, Claudio
The Botanical Drug PBI-05204, a Supercritical CO2 Extract of Nerium Oleander, Inhibits Growth of Human Glioblastoma, Reduces Akt/mTOR Activities, and Modulates GSC Cell-Renewal Properties 1-gen-2020 Colapietro, A.; Yang, P.; Rossetti, A.; Mancini, A.; Vitale, F.; Martellucci, S.; Conway, T. L.; Chakraborty, S.; Marampon, F.; Mattei, V.; Gravina, G. L.; Biordi, A. L.; Wei, D.; Newman, R. A.; Festuccia, C.
The brain penetrating and dual TORC1/TORC2 inhibitor, RES529, elicits anti-glioma activity and enhances the therapeutic effects of anti-angiogenetic compounds in preclinical murine models 1-gen-2019 Gravina, Giovanni Luca; Mancini, Andrea; Colapietro, Alessandro; Delle Monache, Simona; Sferra, Roberta; Pompili, Simona; Vitale, Flora; Martellucci, Stefano; Marampon, Francesco; Mattei, Vincenzo; Biordi, Leda; Sherris, David; Festuccia, Claudio
Dual PI3 K/mTOR inhibition reduces prostate cancer bone engraftment altering tumor-induced bone remodeling 1-gen-2018 Mancini, A.; Colapietro, A.; Pompili, S.; Del Fattore, A.; Delle Monache, S.; Biordi, L. A.; Angelucci, A.; Mattei, V.; Liang, C.; Gravina, G. L.; Festuccia, C.
Pharmacological treatment with inhibitors of nuclear export enhances the antitumor activity of docetaxel in human prostate cancer 1-gen-2017 Gravina, Giovanni Luca; Mancini, Andrea; Colapietro, Alessandro; Marampon, Francesco; Sferra, Roberta; Pompili, Simona; Biordi, Leda Assunta; Iorio, Roberto; Flati, Vincenzo; Argueta, Christian; Landesman, Yosef; Kauffman, Michael; Shacham, Sharon; Festuccia, Claudio; Biordi, ASSUNTA LEDA
Increased expression and activity of p75NTR are crucial events in azacitidine-induced cell death in prostate cancer 1-gen-2016 Gravina, GIOVANNI LUCA; Marampon, Francesco; Sanita', Patrizia; Mancini, Andrea; Colapietro, Alessandro; Scarsella, Luca; Jitariuc, Ana; Biordi, ASSUNTA LEDA; Ficorella, Corrado; Festuccia, Claudio
CXCR4 pharmacogical inhibition reduces bone and soft tissue metastatic burden by affecting tumor growth and tumorigenic potential in prostate cancer preclinical models 1-gen-2015 Gravina, GIOVANNI LUCA; Mancini, Andrea; Muzi, Paola; Ventura, Luca; Biordi, ASSUNTA LEDA; Ricevuto, Enrico; Pompili, Simona; Mattei, Claudia; DI CESARE, Ernesto; Jannini, Emmanuele A.; Festuccia, Claudio
Modificazioni strutturali della parete vaginale in donne affette da prolasso genitale (POP) 1-gen-2014 Zanelli, D; D'Alfonso, A; Vetuschi, Antonella; Biordi, ASSUNTA LEDA; Patacchiola, Felice; Carta, Gaspare
INCREASED RADIOSENSITIVITY AFTER ANDROGENIC MANIPULATION IN PROSTATE CANCER CELL MODELS 1-gen-2013 Festuccia, C; Gravina, GIOVANNI LUCA; Mancini, A; Marampon, F; Biordi, ASSUNTA LEDA; Vittorini, F; Lenzi, A; Jannini, E.
HORMONE TREATMENT PROMOTES CASTRATION-RESISTANT PHENOTYPE BY INCREASING PI3K/AKT ACTIVITY IN PROSTATE CANCER MODELS. PRECLINICAL DATA ON COMBINED PHOSPHATIDYLINOSITOL-3-KINASE/MTOR INHIBITION WITH ENDOCRINE THERAPY FOR ANDROGEN RECEPTOR-POSITIVE PROSTATE CANCER CELLS 1-gen-2013 Festuccia, C; Gravina, GIOVANNI LUCA; Mancini, A; Marampon, F; Biordi, ASSUNTA LEDA; Piccolella, M; Motta, M; Sherris, D; Lenzi, A; Jannini, E. A.
The TORC1/TORC2 inhibitor, Palomid 529, reduces tumor growth and sensitizes to docetaxel and cisplatin in aggressive and hormone-refractory prostate cancer cells. 1-gen-2011 Gravina, GIOVANNI LUCA; Marampon, F; Petini, F; Biordi, ASSUNTA LEDA; Sherris, D; Jannini, Emmanuele; Tombolini, V; Festuccia, C.
Antitumor effects of carnertinib in castration resistant prostate cancer models: A Comparative study with erlotinib. 1-gen-2011 Gravina, GIOVANNI LUCA; Marampon, F; Piccolella, M; Biordi, ASSUNTA LEDA; Ficorella, Corrado; Motta, M; Jannini, Emmanuele; Tombolini, V; Festuccia, C.
Epigenetic modulation of PTEN expression during antiandrogenic therapies in human prostate cancer 1-gen-2009 Gravina, GIOVANNI LUCA; Biordi, ASSUNTA LEDA; Martella, F; Flati, Vincenzo; Ricevuto, Enrico; Ficorella, Corrado; Tombolini, V; Festuccia, C.
Biomolecular characterization of human glioblastoma cells in primary cultures: differentiating and antiangiogenic effects of natural and synthetic PPARgamma agonists 1-gen-2008 Benedetti, E; Galzio, Renato; Cinque, Benedetta; Biordi, ASSUNTA LEDA; D'Amico, Ma; D'Angelo, B; Laurenti, G; Ricci, A; Festuccia, C; Cifone, MARIA GRAZIA; Lombardi, D; Cimini, Anna Maria
Antiproliferative and pro-apoptotic effects of 5-azacytidine in prostate carcinoma cells in vitro involve the recovering of PTEN-mediated Akt activity control and androgen sensitivity 1-gen-2007 Fesuccia, C.; D'Alessandro, Anna Maria; Gravina, GIOVANNI LUCA; Biordi, ASSUNTA LEDA; Speca, S.; Millimaggi, D.; Dolo, Vincenza; Ricevuto, Enrico; Vicentini, Carlo; Bologna, Mauro
Gefitinib and bicalutamide show synergistic effects in primary cultures of prostate cancer derived from androgen-dependent naive patients 1-gen-2007 Festuccia, C; Gravina, GIOVANNI LUCA; Muzi, P; Biordi, ASSUNTA LEDA; Ronchi, P; Martella, O; Vicentini, Carlo; Bologna, Mauro
Crucial pathophysiological role of CXCR2 in experimental ulcerative colitis in mice 1-gen-2007 Buanne, P; DI CARLO, E; Caputi, L; Brandolini, L; Mosca, M; Cattani, F; Pellegrini, L; Biordi, ASSUNTA LEDA; Coletti, G; Sorrentino, C; Fedele, G; Colotta, F; Melillo, G; Bertini, R.
Chemokine MIP-2/CXCL2, acting on CXCR2, induces motor neuron death in primary cultures 1-gen-2007 DE PAOLA, M; Buanne, P; Biordi, ASSUNTA LEDA; Bertini, R; Ghezzi, P; Mennini, T.
Differential expression of the components of the plasminogen activating system in human thyroid tumour derived cell lines and papillary carcinomas 1-gen-2006 Ulisse, S; Baldini, E; Toller, M; Marchioni, E; Giacomelli, L; DE ANTONI, E; Ferretti, E; Marzullo, A; Graziano, Fm; Trimboli, P; Biordi, ASSUNTA LEDA; Curcio, F; Gulino, A; AMBESI IMPIOMBATO, Fs; D'Armiento, M.
The role of CXCR2 activity in the contact hypersensitivity response in mice 1-gen-2006 Cattani, F; Gallese, A; Mosca, M; Buanne, P; Biordi, ASSUNTA LEDA; Francavilla, Sandro; Coletti, G; Pellegrini, L; Melillo, G; Bertini, R.