PICCIRILLI, ALESSANDRA

PICCIRILLI, ALESSANDRA  

Dipartimento di Scienze cliniche applicate e biotecnologiche  

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Amino acid replacement at position 228 induces fluctuation in the Ω-loop of KPC-3 and reduces the affinity against oxyimino cephalosporins: Kinetic and molecular dynamics studies 1-gen-2020 Piccirilli, A.; Brisdelli, F.; Docquier, J. D.; Aschi, M.; Cherubini, S.; De Luca, F.; Matagne, A.; Amicosante, G.; Perilli, M.
Biochemical and molecular characterization of GES and NDM engineered variants: interactions with β-lactams and inhibitors 19-dic-2019 Piccirilli, Alessandra
Biofilm formation among Stenotrophomonas Maltophilia isolates has clinical relevance: The ANSELM prospective multicenter study 1-gen-2021 Pompilio, A.; Ranalli, M.; Piccirilli, A.; Perilli, M.; Vukovic, D.; Savic, B.; Krutova, M.; Drevinek, P.; Jonas, D.; Fiscarelli, E. V.; Assanti, V. T. G.; Tavio, M. M.; Artiles, F.; Di Bonaventura, G.
Deciphering the Role of V88L Substitution in NDM-24 Metallo-β-Lactamase 1-gen-2019 Liu, Z; Piccirilli, A; Liu, D; Li, W; Wang, Y and Shen J
Exploring the role of l10 loop in new delhi metallo-β-lactamase (Ndm-1): Kinetic and dynamic studies 1-gen-2021 Piccirilli, A.; Criscuolo, E.; Brisdelli, F.; Mercuri, P. S.; Cherubini, S.; De Sciscio, M. L.; Maccarrone, M.; Galleni, M.; Amicosante, G.; Perilli, M.
First Identification of β-Lactamases in Antibiotic-Resistant Escherichia coli, Citrobacter freundii, and Aeromonas spp. Isolated in Stream Macroinvertebrates in a Central Italian Region. 1-gen-2020 Segatore, B; Piccirilli, A; Setacci, D; Cicolani, B; Di Sabatino, A; Miccoli, Fp; Perilli, M; Amicosante, G.
Identification of CTX-M-15 and CTX-M-27 in Antibiotic-Resistant Gram-Negative Bacteria Isolated from Three Rivers Running in Central Italy. 1-gen-2019 Piccirilli, A; Pompilio, A; Rossi, L; Segatore, B; Amicosante, G; Rosatelli, G; Perilli, M; Di Bonaventura, G.
Inhibitory Potential of Polyclonal Camel Antibodies against New Delhi Metallo-β-lactamase-1 (NDM-1). 1-gen-2020 Ben Abderrazek, R; Chammam, S; Ksouri, A; Perilli, M; Dhaouadi, S; Mdini, I; Benlasfar, Z; Amicosante, G; Bouhaouala-Zahar, B; Piccirilli, A.
Interaction of carbapenems and β-lactamase inhibitors towards CTX-M-15 and CTX-M-15G238Cmutant 1-gen-2017 Sabatini, Alessia; Brisdelli, Fabrizia; Celenza, Giuseppe; Marcoccia, Francesca; Colapietro, Martina; Tavío, María M.; Piccirilli, Alessandra; Amicosante, Gianfranco; Perilli, Mariagrazia
Kinetic profile and molecular dynamic studies show that Y229W substitution in an NDM-1/L209F variant restores the hydrolytic activity of the enzyme toward penicillins, cephalosporins, and carbapenems 1-gen-2019 Piccirilli, A.; Brisdelli, F.; Aschi, M.; Celenza, G.; Amicosante, G.; Perilli, M.
Kinetic studies on CphA mutants reveal the role of the P158-P172 loop in activity versus carbapenems 1-gen-2016 Bottoni, Carlo; Perilli, Mariagrazia; Marcoccia, Francesca; Piccirilli, Alessandra; Pellegrini, Cristina; Colapietro, Martina; Sabatini, Alessia; Celenza, Giuseppe; Kerff, Frédéric; Amicosante, Gianfranco; Galleni, Moreno; Mercuri, Paola Sandra
Kinetic studies on CphA mutants: the role of the loop P158-P170 on the activity versus carbapenems 1-gen-2016 Bottoni, C; Perilli, M; Marcoccia, F; Piccirilli, A; Pellegrini, C; Colapietro, M; Sabatini, A; Celenza, G; Kerff, F; Amicosante, G; Galleni, M; Mercuri, Ps
Laboratory variants GESG170L, GESG170K, and GESG170H increase carbapenem hydrolysis and confer resistance to clavulanic acid 1-gen-2021 Piccirilli, A.; Mercuri, P. S.; Segatore, B.; Galleni, M.; Brisdelli, F.; Kerff, F.; Amicosante, G.; Perilli, M.
Molecular characterization of carbapenem-resistant Klebsiella pneumoniae ST14 and ST512 causing bloodstream infections in ICU and surgery wards of a tertiary University hospital of Verona (Northern Italy): co-production of KPC-3, OXA-48, and CTX-M-15 β-lactamases. 1-gen-2020 Piccirilli, A; Perilli, M; Piccirilli, V; Segatore, B; Amicosante, G; Maccacaro, L; Bazaj, A; Naso, L; Lo Cascio, G; Cornaglia, G.
Oxygen sparing effect of bacteriotherapy in covid-19 1-gen-2021 Ceccarelli, G.; Marazzato, M.; Celani, L.; Lombardi, F.; Piccirilli, A.; Mancone, M.; Trinchieri, V.; Pugliese, F.; Mastroianni, C. M.; D'Ettorre, G.
P174E substitution in GES-1 and GES-5 β-lactamases improves catalytic efficiency towards carbapenems. 1-gen-2018 Piccirilli, Alessandra; Mercuri Paola, Sandra; Galleni, Moreno; Aschi, Massimiliano; Matagne, Andrè; Amicosante, Gianfranco; Perilli, Mariagrazia
Potent inhibitory activity of taniborbactam towards NDM-1 and NDM-1Q119X mutants, and in vitro activity of cefepime/taniborbactam against MBLs producing Enterobacterales 1-gen-2021 Piccirilli, A.; Segatore, B.; Brisdelli, F.; Amicosante, G.; Perilli, M.
Resistome and Virulome of Multi-Drug Resistant E. coli ST131 Isolated from Residents of Long-Term Care Facilities in the Northern Italian Region 1-gen-2022 Cherubini, S.; Perilli, M.; Azzini, A. M.; Tacconelli, E.; Maccacaro, L.; Bazaj, A.; Naso, L.; Amicosante, G.; Cascio, G. L.; Piccirilli, A.
TEM-184, a Novel TEM-Derived Extended-Spectrum β-Lactamase with Enhanced Activity against Aztreonam 1-gen-2018 Piccirilli A, 1.; Perilli, M; Amicosante, G; Conte, V; Tascini, C; Rossolini, Gm; Giani, T.
Transient disappearance of CD19+/CD5+ B-lymphocyte clone in peripheral blood in a patient with CLL during SARS-CoV-2-related mild disease 1-gen-2021 Barnabei, R.; Di Michele, G.; Cellini, A.; Amicosante, G.; Perilli, M.; Bellio, P.; Piccirilli, A.; Celenza, G.