CINECA IRIS Institutional Research Information System
IRIS è la soluzione IT che facilita la raccolta e la gestione dei dati relativi alle attività e ai prodotti della ricerca. Fornisce a ricercatori, amministratori e valutatori gli strumenti per monitorare i risultati della ricerca, aumentarne la visibilità e allocare in modo efficace le risorse disponibili.
EnglishA tandem gold(I)-catalyzed aminocylization/fluorination and a two-step, one-pot gold(III)-catalyzed cyclization/electrophilic fluorination provide a convenient and general method for the synthesis of 3,3-difluoro-2-substituted-3H-indoles in good yield undermild conditions. Extension of the procedure to the synthesis of 2-aryl-3-fluoro-1H-indoles is described. The reaction proceeds smoothly in green ethanol and does not require any base, acid, or N-protective group.
| Titolo: | One-Pot Gold-Catalyzed Aminofluorination of Unprotected 2-Alkynylanilines | |
| Autori: | ||
| Data di pubblicazione: | 2013 | |
| Rivista: | ||
| Abstract: | A tandem gold(I)-catalyzed aminocylization/fluorination and a two-step, one-pot gold(III)-catalyzed cyclization/electrophilic fluorination provide a convenient and general method for the synthesis of 3,3-difluoro-2-substituted-3H-indoles in good yield undermild conditions. Extension of the procedure to the synthesis of 2-aryl-3-fluoro-1H-indoles is described. The reaction proceeds smoothly in green ethanol and does not require any base, acid, or N-protective group. | |
| Handle: | http://hdl.handle.net/11697/10076 | |
| Appare nelle tipologie: | 1.1 Articolo in rivista |
File in questo prodotto:
http://hdl.handle.net/11697/10076
Copyright © 2021