As the most common form of skin cancer, basal cell carcinoma (BCC) is typified by locally infiltrative growth and a very low risk of metastasis. On occasion, however, this otherwise indolent neoplasm may behave aggressively, demonstrating deep tissue invasion and a high rate of postsurgical recurrence. The pathogenesis and determinants of such tenacious growth are not completely understood. Only 1% of all BCC's achieve the status of 'giant', as defined in 1988 by the American Joint Committee on Cancer. In this article, the authors provide a comprehensive review of the scientific literature on giant basal cell carcinoma (GBCC) of the skin and report their experience with this rare tumour subtype.
Titolo: | Giant basal cell carcinoma of the skin: literature review and personal experience. |
Autori: | |
Data di pubblicazione: | 2012 |
Rivista: | |
Handle: | http://hdl.handle.net/11697/10606 |
Appare nelle tipologie: | 1.1 Articolo in rivista |