A simple and precise high-performance liquid procedure has been developed for the determination of Ofloxacin (DL-8280), a new oxazine derivative in human serum, urine and bile using Norfloxacin as internal standard. The work-up procedure involves a chemical extraction step followed by isocratic chromatography on a anion-exchange analytical column, with ultraviolet detection. The run time for the assay was 11.5 minutes. © 1986, Taylor & Francis Group, LLC. All rights reserved.
|Titolo:||Determination of ofloxacin, a new oxazine derivative in human serum, urine, and bile by high-performance liquid chromatography|
|Autori interni:||GUADAGNI, Stefano|
|Data di pubblicazione:||1986|
|Rivista:||JOURNAL OF LIQUID CHROMATOGRAPHY|
|Appare nelle tipologie:||1.1 Articolo in rivista|