The first synthesis of a series of totally orthogonal protected racemic R-(trifluoromethyl)- and R-(difluoromethyl)arginines is described. The key steps of the synthesis are the mild guanidinylation procedure and the selective hydrogenation of a CC triple bond in the presence of a Cbz-group.
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http://hdl.handle.net/11697/11601
Titolo: | First Synthesis of Totally Orthogonal Protected alpha-(Trifluoromethyl)- and alpha-(Difluoromethyl)arginines |
Autori: | |
Data di pubblicazione: | 2001 |
Rivista: | |
Abstract: | The first synthesis of a series of totally orthogonal protected racemic R-(trifluoromethyl)- and R-(difluoromethyl)arginines is described. The key steps of the synthesis are the mild guanidinylation procedure and the selective hydrogenation of a CC triple bond in the presence of a Cbz-group. |
Handle: | http://hdl.handle.net/11697/11601 |
Appare nelle tipologie: | 1.1 Articolo in rivista |
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