CINECA IRIS Institutional Research Information System
IRIS è la soluzione IT che facilita la raccolta e la gestione dei dati relativi alle attività e ai prodotti della ricerca. Fornisce a ricercatori, amministratori e valutatori gli strumenti per monitorare i risultati della ricerca, aumentarne la visibilità e allocare in modo efficace le risorse disponibili.
EnglishA new electrochemical method for the mild generation of naked beta-dicarbonyl derivative enolates is disclosed. The electrolysis, under galvanostatic control. of a solution of N-acetoacetyloxazolidin-2-ones acetonitrile tetraethylammonium perchlorate allowed the selective alpha-monoalkylation of the 1.3-dicarbonyl residue with a variety of alkyl halides, in very good yields and short reaction times. More interestingly. no by-products arising from either the electroreduction of the carbonyl functionalities or from nucleophilic cyanomethyl anion attack were detected.
| Titolo: | Electrochemical generation of tetraethylammonium N-acetoacetyloxazolidin-2-one enolates: an easy access to alpha-alkylated acetoacetic derivatives |
| Autori: | |
| Data di pubblicazione: | 2002 |
| Rivista: | |
| Abstract: | A new electrochemical method for the mild generation of naked beta-dicarbonyl derivative enolates is disclosed. The electrolysis, under galvanostatic control. of a solution of N-acetoacetyloxazolidin-2-ones acetonitrile tetraethylammonium perchlorate allowed the selective alpha-monoalkylation of the 1.3-dicarbonyl residue with a variety of alkyl halides, in very good yields and short reaction times. More interestingly. no by-products arising from either the electroreduction of the carbonyl functionalities or from nucleophilic cyanomethyl anion attack were detected. |
| Handle: | http://hdl.handle.net/11697/11753 |
| Appare nelle tipologie: | 1.1 Articolo in rivista |
File in questo prodotto:
Copyright © 2018