The cyclization of 2-alkynylanilines in the presence of PdCl2 and nBu4NCl under an acidic CH2Cl2-HCI two-phase system affords 2-substituted indoles in good to high yield, at room temperature. The reaction is particularly suited to the one-flask preparation of 2-substituted indoles from 2-ethynylaniline.
Palladium-catalysed cyclization of 2-alkynylanilines to 2-substituted indoles under an acidic two-phase system
CARNICELLI, VERONICA;MARINELLI, Fabio
1994-01-01
Abstract
The cyclization of 2-alkynylanilines in the presence of PdCl2 and nBu4NCl under an acidic CH2Cl2-HCI two-phase system affords 2-substituted indoles in good to high yield, at room temperature. The reaction is particularly suited to the one-flask preparation of 2-substituted indoles from 2-ethynylaniline.File in questo prodotto:
Non ci sono file associati a questo prodotto.
Pubblicazioni consigliate
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
