An aldol-reduction one-pot sequence allows syn-syn polyketide fragments such as 7 to be obtained enantio and diastereoselectively. Enol Diisopinocampheylborinate is able to influence both the aldol and the subsequent reduction with NaBH4, via a chelate chair like intermediate.
Boron Mediated One-Pot Aldol-reduction Sequence: Enantio and Diastereoselective Synthesis of Typical Polyketide Fragments
ROSSI, LEUCIO
1994-01-01
Abstract
An aldol-reduction one-pot sequence allows syn-syn polyketide fragments such as 7 to be obtained enantio and diastereoselectively. Enol Diisopinocampheylborinate is able to influence both the aldol and the subsequent reduction with NaBH4, via a chelate chair like intermediate.File in questo prodotto:
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