(Chemical Equation Presented) The title reaction catalyzed by the commercially available chiral secondary amine 1 proceeds with high stereocontrol and allows the in situ generation of N-carbamate-protected imines from stable a-amido sulfones 2. This organocatalytic approach provides easy and convenient access to valuable compounds 3 in high yield, with very good anti selectivity,and in high enantiomeric purity. © 2008 Wiley-VCH Verlag GmbH & Co. KGaA.

Aminocatalytic enantioselective anti-Mannich reaction of aldehydes with in situ generated N-cbz and N-boc imines

Carlone, Armando;
2008-01-01

Abstract

(Chemical Equation Presented) The title reaction catalyzed by the commercially available chiral secondary amine 1 proceeds with high stereocontrol and allows the in situ generation of N-carbamate-protected imines from stable a-amido sulfones 2. This organocatalytic approach provides easy and convenient access to valuable compounds 3 in high yield, with very good anti selectivity,and in high enantiomeric purity. © 2008 Wiley-VCH Verlag GmbH & Co. KGaA.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11697/121169
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