The first Lewis acid catalyzed protection of alcohols as Boc derivatives is described. Zinc acetate is a very efficient catalyst for this transformation and the reaction can be applied to primary, secondary and aromatic alcohols, providing the first example of a generally applicable method. © Georg Thieme Verlag Stuttgart.
The first simple method of protection of hydroxy compounds as their O-Boc derivatives under Lewis acid catalysis
Carlone, Armando;
2006-01-01
Abstract
The first Lewis acid catalyzed protection of alcohols as Boc derivatives is described. Zinc acetate is a very efficient catalyst for this transformation and the reaction can be applied to primary, secondary and aromatic alcohols, providing the first example of a generally applicable method. © Georg Thieme Verlag Stuttgart.File in questo prodotto:
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