The use of a bifunctional Cinchona alkaloid catalyst has provided a new organocatalytic strategy for the enantioselective addition of diphenylphosphine to a range of nitroalkenes, affording optically active Î²-nitrophosphines (up to 99% ee after crystallization); this organocatalytic approach, providing a direct route to a new class of potentially useful enantiopure P,N-ligands, constitutes a bridge between the two complementary areas of asymmetric catalysis: organo- and metal-catalyzed transformations. Â© The Royal Society of Chemistry.
|Titolo:||Organocatalytic asymmetric hydrophosphination of nitroalkenes|
|Data di pubblicazione:||2007|
|Appare nelle tipologie:||1.1 Articolo in rivista|