Optically active 2,5-disubstituted-cyclohexen-2-one derivatives have been prepared in a one-pot process consisting of five reaction steps: an organocatalytic asymmetric conjugated addition of Î²-ketoesters to Î±,Î²-unsaturated aldehydes that proceeds in aqueous solutions or under solvent-free conditions has been implemented in a multi-step process. Â© The Royal Society of Chemistry.
|Titolo:||A simple asymmetric organocatalytic approach to optically active cyclohexenones|
|Data di pubblicazione:||2006|
|Appare nelle tipologie:||1.1 Articolo in rivista|