A practical metal-free approach to the synthesis of 2-aroyl-N-tosyl-1H-indole-3 carboxamides through an unprecedented sequential 5-endo-dig cycloamination /carboxamidation reaction of β-(2-aminophenyl)-α,β-ynones with the tosyl isocyanate is described. A computational model gives a plausible rationale for the unexpected results.
Reaction of β-(2-aminophenyl)-α,β-Ynones with Tosyl Isocyanate: Experimental and Computational Investigations
Rode, N. D.;Aschi, M.;Chiarini, M.;Del Vecchio, L.;Marinelli, F.;Arcadi, A.
2018-01-01
Abstract
A practical metal-free approach to the synthesis of 2-aroyl-N-tosyl-1H-indole-3 carboxamides through an unprecedented sequential 5-endo-dig cycloamination /carboxamidation reaction of β-(2-aminophenyl)-α,β-ynones with the tosyl isocyanate is described. A computational model gives a plausible rationale for the unexpected results.File in questo prodotto:
Non ci sono file associati a questo prodotto.
Pubblicazioni consigliate
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
