The first enantioselective Michael addition of aniline to chalcones was promoted by cheap and commercially available chincona alkaloids under solvent-free conditions. Variously substituted chalcones were examined as substrates giving the conjugate adducts in moderate to good enantioselectivity. The simple experimental procedure had no work-up and short reaction times, which are the notable advantages.

Organocatalytic asymmetric aza-Michael addition of aniline to chalcones under sonlvent-free conditions

PALOMBI L.;
2008-01-01

Abstract

The first enantioselective Michael addition of aniline to chalcones was promoted by cheap and commercially available chincona alkaloids under solvent-free conditions. Variously substituted chalcones were examined as substrates giving the conjugate adducts in moderate to good enantioselectivity. The simple experimental procedure had no work-up and short reaction times, which are the notable advantages.
File in questo prodotto:
Non ci sono file associati a questo prodotto.

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11697/145721
Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus 47
  • ???jsp.display-item.citation.isi??? 43
social impact