The palladium-catalyzed reaction of aryl and heteroaryl bromides and triflates with o-alkynyltrifluoroacetanilides affords 2-substituted 3-aryl- and heteroarylindoles usually in excellent yield. The procedure can be applied to the synthesis of 2-substituted indole-3-carboxaldehydes.

2-Substituted 3-aryl- and 3- heteroarylindoles by the palladium-catalyzed reaction of o- trifluoroacetanilides with aryl bromides

MARINELLI, Fabio;
2003

Abstract

The palladium-catalyzed reaction of aryl and heteroaryl bromides and triflates with o-alkynyltrifluoroacetanilides affords 2-substituted 3-aryl- and heteroarylindoles usually in excellent yield. The procedure can be applied to the synthesis of 2-substituted indole-3-carboxaldehydes.
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/11697/15217
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