The potential role of PTI-1, in the natural story of prostate adenocarcinoma remains to be fullydetermined. PTI-1 expression was evaluated in human prostate cancer cell lines and in paraffinembeddedarchive tissues. PTI-1 expression was found in Mycoplasma infected but not in noninfectedcells. The lack of PTI-1 expression was also confirmed in fixed and paraffin-embeddedhuman cancer prostate biopsies. The overall data indicate that, in prostate tumor cell lines, PTI-1 presence parallels Mycoplasma infection suggesting that PTI-1 might not necessarily play amajor role in the onset of prostate tumorigenesis.
Titolo: | Prostate Tumour-Inducing gene-1 analysis in human prostate cancer cells and tissue in relation to Mycoplasma infection |
Autori: | |
Data di pubblicazione: | 2008 |
Rivista: | |
Abstract: | The potential role of PTI-1, in the natural story of prostate adenocarcinoma remains to be fullydetermined. PTI-1 expression was evaluated in human prostate cancer cell lines and in paraffinembeddedarchive tissues. PTI-1 expression was found in Mycoplasma infected but not in noninfectedcells. The lack of PTI-1 expression was also confirmed in fixed and paraffin-embeddedhuman cancer prostate biopsies. The overall data indicate that, in prostate tumor cell lines, PTI-1 presence parallels Mycoplasma infection suggesting that PTI-1 might not necessarily play amajor role in the onset of prostate tumorigenesis. |
Handle: | http://hdl.handle.net/11697/156743 |
Appare nelle tipologie: | 1.1 Articolo in rivista |
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