CINECA IRIS Institutional Research Information System
IRIS è la soluzione IT che facilita la raccolta e la gestione dei dati relativi alle attività e ai prodotti della ricerca. Fornisce a ricercatori, amministratori e valutatori gli strumenti per monitorare i risultati della ricerca, aumentarne la visibilità e allocare in modo efficace le risorse disponibili.
EnglishA three-step procedure for the preparation of 2-substituted 2-methoxycarbonyl-4-pentynoic acids starting from Meldrum's acid (2,2-dimethyl-1,3-dioxane-4,6-dione) was developed (10 examples). The method is based on the monoalkylation of Meldrum's acid, propargylation of the monoalkyl derivative in the presence of potassium carbonate at room temperature, and treatment of the disubstituted Meldrum's acid with sodium methoxide at room temperature.
| Titolo: | A CONVENIENT ROUTE TO 2,2-DISUBSTITUTED 4-PENTYNOIC ACIDS FROM MELDRUM ACID | |
| Autori: | ||
| Data di pubblicazione: | 1991 | |
| Rivista: | ||
| Abstract: | A three-step procedure for the preparation of 2-substituted 2-methoxycarbonyl-4-pentynoic acids starting from Meldrum's acid (2,2-dimethyl-1,3-dioxane-4,6-dione) was developed (10 examples). The method is based on the monoalkylation of Meldrum's acid, propargylation of the monoalkyl derivative in the presence of potassium carbonate at room temperature, and treatment of the disubstituted Meldrum's acid with sodium methoxide at room temperature. | |
| Handle: | http://hdl.handle.net/11697/16859 | |
| Appare nelle tipologie: | 1.1 Articolo in rivista |
File in questo prodotto:
Copyright © 2022