Activation of Fas signaling has been associated with the development of cardiomyocyte hypertrophy. In the present study, we investigated the effects of increased expression of c-Flip, a natural modulator of Fas receptor signaling, in a mouse model of cardiac growth response to pressure overload.

c-Flip overexpression reduces cardiac hypertrophy in response to pressure overload

DE CESARIS, Paola;
2008-01-01

Abstract

Activation of Fas signaling has been associated with the development of cardiomyocyte hypertrophy. In the present study, we investigated the effects of increased expression of c-Flip, a natural modulator of Fas receptor signaling, in a mouse model of cardiac growth response to pressure overload.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11697/19123
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