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EnglishA novel MICA allele, MICA*078, has been identified during HLA/MICA high resolution typing of Moroccan patients with celiac disease. MICA*078 shows an uncommon variation at a highly conserved nucleotide position (nt 493, G→A), resulting in one amino acid change at codon 142 (V→I) of MICA gene (compared to MICA*002:01), located in the α2-domain, in which V142 is the common residue. © 2015 American Society for Histocompatibility and Immunogenetics.
http://hdl.handle.net/11697/1951| Titolo: | MICA∗078: A novel allele identified in a moroccan individual affected by celiac disease. |
| Autori interni: | TESSITORE, ALESSANDRA |
| Data di pubblicazione: | 2015 |
| Rivista: | HUMAN IMMUNOLOGY |
| Abstract: | A novel MICA allele, MICA*078, has been identified during HLA/MICA high resolution typing of Moroccan patients with celiac disease. MICA*078 shows an uncommon variation at a highly conserved nucleotide position (nt 493, G→A), resulting in one amino acid change at codon 142 (V→I) of MICA gene (compared to MICA*002:01), located in the α2-domain, in which V142 is the common residue. © 2015 American Society for Histocompatibility and Immunogenetics. |
| Handle: | http://hdl.handle.net/11697/1951 |
| Appare nelle tipologie: | 1.1 Articolo in rivista |
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