A novel MICA allele, MICA*078, has been identified during HLA/MICA high resolution typing of Moroccan patients with celiac disease. MICA*078 shows an uncommon variation at a highly conserved nucleotide position (nt 493, G→A), resulting in one amino acid change at codon 142 (V→I) of MICA gene (compared to MICA*002:01), located in the α2-domain, in which V142 is the common residue. © 2015 American Society for Histocompatibility and Immunogenetics.
MICA∗078: A novel allele identified in a moroccan individual affected by celiac disease.
TESSITORE, ALESSANDRA;
2015-01-01
Abstract
A novel MICA allele, MICA*078, has been identified during HLA/MICA high resolution typing of Moroccan patients with celiac disease. MICA*078 shows an uncommon variation at a highly conserved nucleotide position (nt 493, G→A), resulting in one amino acid change at codon 142 (V→I) of MICA gene (compared to MICA*002:01), located in the α2-domain, in which V142 is the common residue. © 2015 American Society for Histocompatibility and Immunogenetics.File in questo prodotto:
File | Dimensione | Formato | |
---|---|---|---|
Piancatelli_2015.pdf
solo utenti autorizzati
Tipologia:
Documento in Versione Editoriale
Licenza:
Copyright dell'editore
Dimensione
1.46 MB
Formato
Adobe PDF
|
1.46 MB | Adobe PDF | Visualizza/Apri Richiedi una copia |
Pubblicazioni consigliate
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.