A novel MICA allele, MICA*078, has been identified during HLA/MICA high resolution typing of Moroccan patients with celiac disease. MICA*078 shows an uncommon variation at a highly conserved nucleotide position (nt 493, G→A), resulting in one amino acid change at codon 142 (V→I) of MICA gene (compared to MICA*002:01), located in the α2-domain, in which V142 is the common residue. © 2015 American Society for Histocompatibility and Immunogenetics.
MICA∗078: A novel allele identified in a moroccan individual affected by celiac disease.
TESSITORE, ALESSANDRA;
2015-01-01
Abstract
A novel MICA allele, MICA*078, has been identified during HLA/MICA high resolution typing of Moroccan patients with celiac disease. MICA*078 shows an uncommon variation at a highly conserved nucleotide position (nt 493, G→A), resulting in one amino acid change at codon 142 (V→I) of MICA gene (compared to MICA*002:01), located in the α2-domain, in which V142 is the common residue. © 2015 American Society for Histocompatibility and Immunogenetics.File in questo prodotto:
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