N-Boc derivatives of Met, Cys, and Trp, the properties of which resemble those of the respective amino acid residues present in proteins, are efficiently oxidized by methyltrioxorhenium and H2O2. A high regioselectivity for the oxidation of these residues when embedded into peptides was also found.

A Novel Oxidative Side-Chain Transformation of -Amino Acids and Peptides by Methyltrioxorhenium/H2O2 system

CRUCIANELLI, MARCELLO;DE ANGELIS, Francesco;
2004

Abstract

N-Boc derivatives of Met, Cys, and Trp, the properties of which resemble those of the respective amino acid residues present in proteins, are efficiently oxidized by methyltrioxorhenium and H2O2. A high regioselectivity for the oxidation of these residues when embedded into peptides was also found.
File in questo prodotto:
Non ci sono file associati a questo prodotto.

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11697/19573
Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus 21
  • ???jsp.display-item.citation.isi??? 22
social impact