N-Boc derivatives of Met, Cys, and Trp, the properties of which resemble those of the respective amino acid residues present in proteins, are efficiently oxidized by methyltrioxorhenium and H2O2. A high regioselectivity for the oxidation of these residues when embedded into peptides was also found.

A Novel Oxidative Side-Chain Transformation of -Amino Acids and Peptides by Methyltrioxorhenium/H2O2 system

CRUCIANELLI, MARCELLO;DE ANGELIS, Francesco;
2004-01-01

Abstract

N-Boc derivatives of Met, Cys, and Trp, the properties of which resemble those of the respective amino acid residues present in proteins, are efficiently oxidized by methyltrioxorhenium and H2O2. A high regioselectivity for the oxidation of these residues when embedded into peptides was also found.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11697/19573
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