The development of micellar catalysis offers a sustainable alternative to organic solvents representing an environmental milestone in organic synthesis. Here the first Michael addition of masked acetaldehyde under neutral, cationic and anionic micellar catalysis is reported, affording the products in high yields and enantiomeric excess in spite the use of water as solvent.
Organocatalytic synthesis of γ-amino acids precursors via masked acetaldehyde under micellar catalysis
Giorgianni, Giuliana;Allegritti, Elena;Giansanti, Luisa
;Carlone, Armando
Conceptualization
;Pesciaioli, Fabio
Project Administration
2022-01-01
Abstract
The development of micellar catalysis offers a sustainable alternative to organic solvents representing an environmental milestone in organic synthesis. Here the first Michael addition of masked acetaldehyde under neutral, cationic and anionic micellar catalysis is reported, affording the products in high yields and enantiomeric excess in spite the use of water as solvent.File in questo prodotto:
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2023 Organocatalytic via Masked Acetaldehyde Micelles _SynOpen.pdf
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