Aim: The aim of the study is basically to underline the advantages of the digital approach for the diagnosis, the treatment plan and the surgical and orthodontic treatment in the patients affected by ameloblastoma. Materials and methods: A patient affected by ameloblastoma of the upper maxilla underwent to a digital approach for the exact diagnosis and the virtual planning of the post-surgery orthodontic treatment using aligners. A 3D computer tomography was used to a precise detection of the anatomical limits of the neoformation. A concomitant myofunctional therapy was performed with a complete occlusal and functional restoration. Results: A complete alignment of the residual dentition was achieved. The functional and esthetic outcome was completed using a temporary removable prosthesis waiting for a bone grafting and implant supported fixed restoration. Conclusion: In patients with ameloblastoma the digital approach for a correct diagnosis and treatment planning with aligner can be extremely useful for a detailed control of the orthodontic movements together with an accurate virtual and clinical control of all the aspect that can interfere with the occlusion.
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