A new approach to the Friedländer synthesis of quinolines is described. Polysubstituted quinolines are readily prepared under milder conditions than in other existing methods through a gold(III)-catalysed sequential condensation/annulation reaction of o-amino aromatic carbonyls and ketones containing active methylene groups.

A new green approach to the Friedlander synthesis of quinolines

ARCADI, Antonio;MARINELLI, Fabio
2003-01-01

Abstract

A new approach to the Friedländer synthesis of quinolines is described. Polysubstituted quinolines are readily prepared under milder conditions than in other existing methods through a gold(III)-catalysed sequential condensation/annulation reaction of o-amino aromatic carbonyls and ketones containing active methylene groups.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11697/23217
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