A strongly improved, highly stereoselective synthesis of (S)-α-trifluoromethyl aspartic acid via addition of lithium malonate to a chiral sulfinimine of trifluoropyruvate is presented.
Mannich-type Reaction of Methylene Active Compounds with a Chiral Sulfinimine of Trifluoropyruvate: New Highly Stereoselective Synthesis of (S)--Trifluoromethyl-Aspartic Acid
CRUCIANELLI, MARCELLO;DE ANGELIS, Francesco;
2005-01-01
Abstract
A strongly improved, highly stereoselective synthesis of (S)-α-trifluoromethyl aspartic acid via addition of lithium malonate to a chiral sulfinimine of trifluoropyruvate is presented.File in questo prodotto:
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