Key mutations in the C-terminus of the HBV surface glycoprotein correlate with lower HBsAg levels in vivo, hinder HBsAg secretion in vitro and reduce HBsAg structural stability in the setting of HBeAg-negative chronic HBV genotype- infection

Salpini R;Battisti A;Piermatteo L;Carioti L;Anastasiou OE;Gill US;Carlo DD;Colagrossi L;Duca L;Bertoli A;La Rosa KY;Fabeni L;Iuvara A;Malagnino V;Cerva C;Lichtner M;Mastroianni CM;De Sanctis GM;Paoloni M;Marignani M;Pasquazzi C;Iapadre N;Parruti G;Vecchiet J;Sarmati L;Andreoni M;Angelico M;Grelli S;Kennedy P;Verheyen J;Aquaro S;Silberstein FC;Perno CF;Svicher V

2020-01-01