Palladium-catalysed reactions of aryl iodides/vinyl triflates with 2,2,2-trifluoro-N-(2-(4-[2,2,2-trifluoro-acetylamino)-phenyl]buta-1,3-diynyl)-phenyl)-acetamide provide a straightforward entry into 3,3'-disubstituted-2,2'-biindolyls. Subsequent application of the procedure to homochiral aryl iodides affords the corresponding chiral 3,3'-disubstituted-2,2'-biindolyls. The methodology can also be applied to the synthesis of benzo[c]indolo[2,3-a]carbazoles.
Synthesis of 3,3-disubstituted-2,2-biindolyls through sequential palladium-catalysed reactions of 2,2,2-trifluoro-N-(2-(4-[2,2,2-trifluoro-acetylamino)-phenyl]-buta-1,3-diynyl)-phenyl)-acetamide with organic halides/triflates
ARCADI, Antonio;MARINELLI, Fabio;
2006-01-01
Abstract
Palladium-catalysed reactions of aryl iodides/vinyl triflates with 2,2,2-trifluoro-N-(2-(4-[2,2,2-trifluoro-acetylamino)-phenyl]buta-1,3-diynyl)-phenyl)-acetamide provide a straightforward entry into 3,3'-disubstituted-2,2'-biindolyls. Subsequent application of the procedure to homochiral aryl iodides affords the corresponding chiral 3,3'-disubstituted-2,2'-biindolyls. The methodology can also be applied to the synthesis of benzo[c]indolo[2,3-a]carbazoles.File in questo prodotto:
Non ci sono file associati a questo prodotto.
Pubblicazioni consigliate
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
