Type 1A, the most common form of Charcot-Marie-Tooth (CMT1A) disease, is characterized by demyelination of the peripheral nervous system. So far, only a few cases of the disease with concomitant brain white matter lesions have been described. We report an Italian family with CMT1A disease, consisting of the proband and 4 affected members, presenting with concomitant brain white matter lesions at magnetic resonance imaging. The association is particularly fascinating and might depend on an autoimmune mechanism, not yet clarified. Copyright (C) 2004 S. Karger AG, Basel.

Brain white matter lesions in an Italian family with Charcot-Marie–Tooth disease

SACCO, SIMONA;MARINI, Carmine;CAROLEI, ANTONIO
2004-01-01

Abstract

Type 1A, the most common form of Charcot-Marie-Tooth (CMT1A) disease, is characterized by demyelination of the peripheral nervous system. So far, only a few cases of the disease with concomitant brain white matter lesions have been described. We report an Italian family with CMT1A disease, consisting of the proband and 4 affected members, presenting with concomitant brain white matter lesions at magnetic resonance imaging. The association is particularly fascinating and might depend on an autoimmune mechanism, not yet clarified. Copyright (C) 2004 S. Karger AG, Basel.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11697/3097
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