A novel model of numerical thermal dosimetry for vascularized biological tissues exposed to laser sources during hyperthermia treatment techniques is proposed. The comparison between the novel discrete vasculature model and the old Pennes BHE for a simple test case is also investigated. The point to be stressed is that the detailed thermal-geometrical information about the vascular structure is taken into account in a flavor mode without significantly affects the computational degree. The price to be paid is however a higher level of complexity in order to correctly solve both the blood and tissue temperature profiles. Furthermore, the detailed geometrical configuration of the tissue embedded vascular structure must be in some way known inside the computational domain.
3-D thermal model of vascularized tissues for hyperthermia treatment
DE SANTIS, VALERIO;FELIZIANI, MAURO
2008-01-01
Abstract
A novel model of numerical thermal dosimetry for vascularized biological tissues exposed to laser sources during hyperthermia treatment techniques is proposed. The comparison between the novel discrete vasculature model and the old Pennes BHE for a simple test case is also investigated. The point to be stressed is that the detailed thermal-geometrical information about the vascular structure is taken into account in a flavor mode without significantly affects the computational degree. The price to be paid is however a higher level of complexity in order to correctly solve both the blood and tissue temperature profiles. Furthermore, the detailed geometrical configuration of the tissue embedded vascular structure must be in some way known inside the computational domain.Pubblicazioni consigliate
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