The drug diffusion process through an arterial eluting stent is studied with a mathematical model. An exact analytical solution is given in the form of an infinite series expansion. The model addresses the role of four controlling parameters and provides qualitative considerations and a quantitative description for drug transport to evaluate feasibility of new drug delivery strategies, and to estimate dose response.
Drug delivery in biological tissues: an application to the eluting stents
DE MONTE, FILIPPO;
2006-01-01
Abstract
The drug diffusion process through an arterial eluting stent is studied with a mathematical model. An exact analytical solution is given in the form of an infinite series expansion. The model addresses the role of four controlling parameters and provides qualitative considerations and a quantitative description for drug transport to evaluate feasibility of new drug delivery strategies, and to estimate dose response.File in questo prodotto:
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