Although estrogen’s effects on sex behavior in mammals are well known, its role on other behaviors, including cognition, have only recently been recognized. This review summarizes work conducted in our laboratory and others toward identifying estrogen’s actions on cognitive functions. The first section will briefly describe the neurobiology of estrogen The second section will discuss estrogen’s effects on cognitive behaviors in mammals, as well as the physiological relevance of these effects and their applicability to human health and disease. The third section will detail the role of estrogen on working memory in humans and non human primates, and in rodents. Finally, the concluding section will briefly describe the relations between estrogen and the aging brain.
Estrogen and cognitive functions
GASBARRI, Antonella;POMPILI, ASSUNTA;
2009-01-01
Abstract
Although estrogen’s effects on sex behavior in mammals are well known, its role on other behaviors, including cognition, have only recently been recognized. This review summarizes work conducted in our laboratory and others toward identifying estrogen’s actions on cognitive functions. The first section will briefly describe the neurobiology of estrogen The second section will discuss estrogen’s effects on cognitive behaviors in mammals, as well as the physiological relevance of these effects and their applicability to human health and disease. The third section will detail the role of estrogen on working memory in humans and non human primates, and in rodents. Finally, the concluding section will briefly describe the relations between estrogen and the aging brain.Pubblicazioni consigliate
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