The ozonolysis of Delta(2)-cephem derivatives 1, 2, and 3, to obtain highly functionalized 2-oxoazetidine and 2-oxoazetidine-4-sulfenic acid derivatives is described. An efficient and selective synthesis of the oxapenem derivative 16 is also reported.
Studies on the Reactivity of Cephalosporins. 6 Ozonolysis of A2-Cephem Derivatives as a New Entry to Highly Functionalized 2-Oxoazetidine and 2-Oxoazetidine-4-sulfenic Acid Derivatives.
CRUCIANELLI, MARCELLO;
1996-01-01
Abstract
The ozonolysis of Delta(2)-cephem derivatives 1, 2, and 3, to obtain highly functionalized 2-oxoazetidine and 2-oxoazetidine-4-sulfenic acid derivatives is described. An efficient and selective synthesis of the oxapenem derivative 16 is also reported.File in questo prodotto:
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