Preliminary results of an original approach to 4-substituted-2-phenylimidazoles starting from readily available N-propargyl-benzamidine and aryl halides are reported. Best yields were obtained using aryl halides bearing an electron-withdrawing group. Plausible mechanisms are also discussed.
Palladium Catalyzed Synthesis of 4-Substituted-2-phenylimidazoles from N- Propargyl-benzamidine
ARCADI, Antonio;
2007-01-01
Abstract
Preliminary results of an original approach to 4-substituted-2-phenylimidazoles starting from readily available N-propargyl-benzamidine and aryl halides are reported. Best yields were obtained using aryl halides bearing an electron-withdrawing group. Plausible mechanisms are also discussed.File in questo prodotto:
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