Efficient Synthesis of Novel Polyfunctionalised 4,5’-Bithiazol-4’-ol Derivatives

Arcadi, A; Attanasi, O A; Filippone, P; Perrulli, Fr; Rossi, E; Santeusanio, S

doi:10.1055/s-2004-835629

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2-Thiazolin-4-one derivatives, obtained by reaction of 14 tert-butyl (3-methoxy-1-methyl-3-oxoprop-1-enyl)diazenecarboxylate with aryl thioamides, were transformed into 5-brornoacetyl-4-hydroxythiazole derivatives by polymer-supported reagents and simple work-up procedures. The compounds thus synthesised were coupled with thioamides bearing valuable functional groups affording novel polyfunctionalised 4,5'-bithiazol-4'-ol derivatives.

Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/11697/7818

Titolo:	Efficient Synthesis of Novel Polyfunctionalised 4,5’-Bithiazol-4’-ol Derivatives
Autori interni:	ARCADI, Antonio
Data di pubblicazione:	2004
Rivista:	SYNLETT
Abstract:	2-Thiazolin-4-one derivatives, obtained by reaction of 14 tert-butyl (3-methoxy-1-methyl-3-oxoprop-1-enyl)diazenecarboxylate with aryl thioamides, were transformed into 5-brornoacetyl-4-hydroxythiazole derivatives by polymer-supported reagents and simple work-up procedures. The compounds thus synthesised were coupled with thioamides bearing valuable functional groups affording novel polyfunctionalised 4,5'-bithiazol-4'-ol derivatives.
Handle:	http://hdl.handle.net/11697/7818
Appare nelle tipologie:	1.1 Articolo in rivista

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