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English2-Thiazolin-4-one derivatives, obtained by reaction of 14 tert-butyl (3-methoxy-1-methyl-3-oxoprop-1-enyl)diazenecarboxylate with aryl thioamides, were transformed into 5-brornoacetyl-4-hydroxythiazole derivatives by polymer-supported reagents and simple work-up procedures. The compounds thus synthesised were coupled with thioamides bearing valuable functional groups affording novel polyfunctionalised 4,5'-bithiazol-4'-ol derivatives.
| Titolo: | Efficient Synthesis of Novel Polyfunctionalised 4,5’-Bithiazol-4’-ol Derivatives |
| Autori: | |
| Data di pubblicazione: | 2004 |
| Rivista: | |
| Abstract: | 2-Thiazolin-4-one derivatives, obtained by reaction of 14 tert-butyl (3-methoxy-1-methyl-3-oxoprop-1-enyl)diazenecarboxylate with aryl thioamides, were transformed into 5-brornoacetyl-4-hydroxythiazole derivatives by polymer-supported reagents and simple work-up procedures. The compounds thus synthesised were coupled with thioamides bearing valuable functional groups affording novel polyfunctionalised 4,5'-bithiazol-4'-ol derivatives. |
| Handle: | http://hdl.handle.net/11697/7818 |
| Appare nelle tipologie: | 1.1 Articolo in rivista |
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