The biocatalytic desymmetrization, in presence of different enzymes, of two models of polyfunctionalized diols in a meso form was studied. PFL was found to be the most selective enzyme with excellent results in chemical and optical yield with some of the tested substrates. The obtained chiral building block was utilized for some useful synthetic transformations toward the synthesis of natural products

Enzyme-Catalyzed Desymmetrization of meso-Skipped Polyols to Useful Chiral Building Blocks

ROSSI, LEUCIO
1993-01-01

Abstract

The biocatalytic desymmetrization, in presence of different enzymes, of two models of polyfunctionalized diols in a meso form was studied. PFL was found to be the most selective enzyme with excellent results in chemical and optical yield with some of the tested substrates. The obtained chiral building block was utilized for some useful synthetic transformations toward the synthesis of natural products
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11697/8170
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