Chemotherapeutically Induced Cutaneous Tuberculosis after BCG Injection in a Patient with Pelvic Osteosarcoma.

"Background: Tuberculosis (TB) is a serious infection afflicting a multitude of people worldwide. Recently, its. prevalence has increased. The incidence of skin involvement generally is low. Bacillus Calmette-Gue´rin (BCG) is. a live attenuated strain of Mycobacterium bovis that typically is administered as a vaccine to stimulate the immune. system when treating some early neoplasms or to guard against tuberculosis.. Methods: Case report and literature review.. Case Report: The authors describe a young man with osteosarcoma of the left hemipelvis who received intradermal. BCG injection for immune stimulation prior to surgery. In the course of neoadjuvant chemotherapy, he. developed cutaneous tuberculosis.. Conclusion: It is our opinion that BCG injection should be avoided in all patients requiring surgery, especially in. oncologic patients, where the immunodeficiency brought on by chemotherapy predisposes to active opportunistic. infection."