"An operationally simple procedure, involving conjugate addition of NaI to b-(2-aminophenyl)-a,b-ynones\/cyclization\/Pd-catalyzed reaction with 2-alkynyl-trifluoroacetanilides afforded 4-(1H-indol-3-yl)quinolines. The whole process was carried out in the same flask, without any intermediate work-up and using ethanol as solvent."
A Concise One-pot Approach to the Synthesis of 4-(1H-indol-3-yl)quinolines
ARCADI, Antonio;MARINELLI, Fabio;
2011-01-01
Abstract
"An operationally simple procedure, involving conjugate addition of NaI to b-(2-aminophenyl)-a,b-ynones\/cyclization\/Pd-catalyzed reaction with 2-alkynyl-trifluoroacetanilides afforded 4-(1H-indol-3-yl)quinolines. The whole process was carried out in the same flask, without any intermediate work-up and using ethanol as solvent."File in questo prodotto:
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