RUGGERI, PIERDOMENICO
RUGGERI, PIERDOMENICO
Molecular Characterization and Inhibition of a Novel Stress-Induced Mitochondrial Protecting Role for Misfolded TrkAIII in Human SH-SY5Y Neuroblastoma Cells
2024-01-01 Cappabianca, Lucia; Ruggieri, Marianna; Sebastiano, Michela; Sbaffone, Maddalena; Martelli, Ilaria; Ruggeri, Pierdomenico; DI PADOVA, Monica; Farina, Antonietta; Mackay, ANDREW REAY
The Alternative TrkAIII Splice Variant, a Targetable Oncogenic Participant in Human Cutaneous Malignant Melanoma
2023-01-01 Cappabianca, Lucia; Zelli, Veronica; Pellegrini, Cristina; Sebastiano, Michela; Maccarone, Rita; Clementi, Marco; Chiominto, Alessandro; Ruggeri, Pierdomenico; Cardelli, Ludovica; Ruggieri, Marianna; Sbaffone, Maddalena; Fargnoli, Maria-Concetta; Guadagni, Stefano; Farina, Antonietta R.; Mackay, Andrew R.
Salvianolic Acid B Strikes Back: New Evidence in the Modulation of Expression and Activity of Matrix Metalloproteinase 9 in MDA-MB-231 Human Breast Cancer Cells
2022-01-01 Ianni, Andrea; Ruggeri, Pierdomenico; Bellio, Pierangelo; Martino, Francesco; Celenza, Giuseppe; Martino, Giuseppe; Franceschini, Nicola
TRKAIII COMMUNICATES ER-STRESS TO THE MITO-CHONDRIA IN NEUROBLASTOMA CELLS, RESULTING INGLYCOLYTIC METABOLIC ADAPTATION
2018-01-01 Farina, A. R.; Cappabianca, L.; Ruggeri, P.; Gneo, L.; Mackay, A. R.
The oncogenic neurotrophin receptor tropomyosin-related kinase variant, TrkAIII
2018-01-01 Farina, Antonietta Rosella; Cappabianca, Lucia; Ruggeri, Pierdomenico; Gneo, Luciana; Pellegrini, Cristina; Fargnoli, Maria-Concetta; Mackay, Andrew Reay
TrkAIII signals endoplasmic reticulum stress to the mitochondria in neuroblastoma cells, resulting in glycolytic metabolic adaptation
2017-01-01 Farina, Antonietta Rosella; Cappabianca, Lucia; Gneo, Luciana; Ruggeri, Pierdomenico; Mackay, Andrew Reay
The enemy from within: Miss-localization of a compromised receptor as a mechanism for TrkAIII oncogenic activity
2016-01-01 Farina, Antonietta; Cappabianca, LUCIA ANNAMARIA; Ruggeri, Pierdomenico; Gneo, Luciana; Mackay, ANDREW REAY
TRAIL induces pro-apoptotic crosstalk between the TRAIL-receptor signaling pathway and TrkAIII in SH-SY5Y cells
2016-01-01 Gneo, Luciana; Ruggeri, Pierdomenico; Cappabianca, LUCIA ANNAMARIA; Farina, Antonietta; Mackay, ANDREW REAY
NGF sensitizes TrkA SH-SY5Y neuroblastoma cells to TRAIL-induced apoptosis
2016-01-01 Ruggeri, Pierdomenico; Cappabianca, LUCIA ANNAMARIA; Farina, Antonietta; Gneo, Luciana; Mackay, ANDREW REAY
NGF Sensitizes TrkA SH-SY5Y Neuroblastoma Cells to TRAIL-Induced Apoptosis
2016-01-01 Gneo, Luciana; Ruggeri, Pierdomenico; Cappabianca, LUCIA ANNAMARIA; Farina, Antonietta; Mackay, ANDREW REAY
TRAIL induces pro-apoptotic crosstalk between the TRAIL-receptor signaling pathway and TRKIII in SH-SY5Y cells, unveiling a potential therapeutic “Achilles heel” for the TrkAIII oncoprotein in neuroblastoma
2016-01-01 Gneo, Luciana; Ruggeri, Pierdomenico; Cappabianca, LUCIA ANNAMARIA; Farina, Antonietta; DI IANNI, Natalia; Mackay, ANDREW REAY
NGF FLIPs TrkA onto the death TRAIL in neuroblastoma cells
2016-01-01 Ruggeri, Pierdomenico; Cappabianca, LUCIA ANNAMARIA; Farina, Antonietta; Gneo, Luciana; Mackay, ANDREW REAY
NGF sensitizes TrKA expressing SH-SY5Y nuroblastoma cells to TRAIL-induced apoptosisi
2015-01-01 Ruggeri, Pierdomenico; Farina, Antonietta; Cappabianca, LUCIA ANNAMARIA; Gneo, Luciana; Mackay, ANDREW REAY
Neurotrophin and Neurotrophin Receptor Involvement in Human Neuroblastoma
2013-01-01 Ruggeri, Pierdomenico; Farina, Antonietta; Cappabianca, LUCIA ANNAMARIA; DI IANNI, Natalia; Ragone, Marzia; Merolle, Stefania; Gulino, A; Mackay, A. R.
TrkAIII promotes microtubule nucleation and assembly at the centrosome in SH-SY5Y neuroblastoma cells, contributing to an undifferentiated anaplastic phenotype.
2013-01-01 Farina, Antonietta; Di Ianni, N; Cappabianca, LUCIA ANNAMARIA; Ruggeri, Pierdomenico; Ragone, M; Ianni, G; Gulino, A; Mackay, ANDREW REAY
Alendronate promotes plasmin-mediated MMP-9 inactivation by exposing cryptic plasmin degradation sites within the MMP-9 catalytic domain.
2012-01-01 Farina, Antonietta; Cappabianca, LUCIA ANNAMARIA; Di Ianni, N; Ruggeri, Pierdomenico; Ragone, M; Merolle, S; Gulino, A; Mackay, ANDREW REAY
Constitutive autotaxin transcription by Nmyc-amplified and non-amplified neuroblastoma cells is regulated by a novel AP-1 and SP-mediated mechanism and abrogated by curcumin
2012-01-01 Farina, Antonietta; Cappabianca, LUCIA ANNAMARIA; Ruggeri, Pierdomenico; Di Ianni, N; Ragone, M; Merolle, S; Sano, K; Stracke, Ml; Horowitz, Jm; Gulino, A; Mackay, ANDREW REAY
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| Molecular Characterization and Inhibition of a Novel Stress-Induced Mitochondrial Protecting Role for Misfolded TrkAIII in Human SH-SY5Y Neuroblastoma Cells | 1-gen-2024 | Cappabianca, Lucia; Ruggieri, Marianna; Sebastiano, Michela; Sbaffone, Maddalena; Martelli, Ilaria; Ruggeri, Pierdomenico; DI PADOVA, Monica; Farina, Antonietta; Mackay, ANDREW REAY | |
| The Alternative TrkAIII Splice Variant, a Targetable Oncogenic Participant in Human Cutaneous Malignant Melanoma | 1-gen-2023 | Cappabianca, Lucia; Zelli, Veronica; Pellegrini, Cristina; Sebastiano, Michela; Maccarone, Rita; Clementi, Marco; Chiominto, Alessandro; Ruggeri, Pierdomenico; Cardelli, Ludovica; Ruggieri, Marianna; Sbaffone, Maddalena; Fargnoli, Maria-Concetta; Guadagni, Stefano; Farina, Antonietta R.; Mackay, Andrew R. | |
| Salvianolic Acid B Strikes Back: New Evidence in the Modulation of Expression and Activity of Matrix Metalloproteinase 9 in MDA-MB-231 Human Breast Cancer Cells | 1-gen-2022 | Ianni, Andrea; Ruggeri, Pierdomenico; Bellio, Pierangelo; Martino, Francesco; Celenza, Giuseppe; Martino, Giuseppe; Franceschini, Nicola | |
| TRKAIII COMMUNICATES ER-STRESS TO THE MITO-CHONDRIA IN NEUROBLASTOMA CELLS, RESULTING INGLYCOLYTIC METABOLIC ADAPTATION | 1-gen-2018 | Farina, A. R.; Cappabianca, L.; Ruggeri, P.; Gneo, L.; Mackay, A. R. | |
| The oncogenic neurotrophin receptor tropomyosin-related kinase variant, TrkAIII | 1-gen-2018 | Farina, Antonietta Rosella; Cappabianca, Lucia; Ruggeri, Pierdomenico; Gneo, Luciana; Pellegrini, Cristina; Fargnoli, Maria-Concetta; Mackay, Andrew Reay | |
| TrkAIII signals endoplasmic reticulum stress to the mitochondria in neuroblastoma cells, resulting in glycolytic metabolic adaptation | 1-gen-2017 | Farina, Antonietta Rosella; Cappabianca, Lucia; Gneo, Luciana; Ruggeri, Pierdomenico; Mackay, Andrew Reay | |
| The enemy from within: Miss-localization of a compromised receptor as a mechanism for TrkAIII oncogenic activity | 1-gen-2016 | Farina, Antonietta; Cappabianca, LUCIA ANNAMARIA; Ruggeri, Pierdomenico; Gneo, Luciana; Mackay, ANDREW REAY | |
| TRAIL induces pro-apoptotic crosstalk between the TRAIL-receptor signaling pathway and TrkAIII in SH-SY5Y cells | 1-gen-2016 | Gneo, Luciana; Ruggeri, Pierdomenico; Cappabianca, LUCIA ANNAMARIA; Farina, Antonietta; Mackay, ANDREW REAY | |
| NGF sensitizes TrkA SH-SY5Y neuroblastoma cells to TRAIL-induced apoptosis | 1-gen-2016 | Ruggeri, Pierdomenico; Cappabianca, LUCIA ANNAMARIA; Farina, Antonietta; Gneo, Luciana; Mackay, ANDREW REAY | |
| NGF Sensitizes TrkA SH-SY5Y Neuroblastoma Cells to TRAIL-Induced Apoptosis | 1-gen-2016 | Gneo, Luciana; Ruggeri, Pierdomenico; Cappabianca, LUCIA ANNAMARIA; Farina, Antonietta; Mackay, ANDREW REAY | |
| TRAIL induces pro-apoptotic crosstalk between the TRAIL-receptor signaling pathway and TRKIII in SH-SY5Y cells, unveiling a potential therapeutic “Achilles heel” for the TrkAIII oncoprotein in neuroblastoma | 1-gen-2016 | Gneo, Luciana; Ruggeri, Pierdomenico; Cappabianca, LUCIA ANNAMARIA; Farina, Antonietta; DI IANNI, Natalia; Mackay, ANDREW REAY | |
| NGF FLIPs TrkA onto the death TRAIL in neuroblastoma cells | 1-gen-2016 | Ruggeri, Pierdomenico; Cappabianca, LUCIA ANNAMARIA; Farina, Antonietta; Gneo, Luciana; Mackay, ANDREW REAY | |
| NGF sensitizes TrKA expressing SH-SY5Y nuroblastoma cells to TRAIL-induced apoptosisi | 1-gen-2015 | Ruggeri, Pierdomenico; Farina, Antonietta; Cappabianca, LUCIA ANNAMARIA; Gneo, Luciana; Mackay, ANDREW REAY | |
| Neurotrophin and Neurotrophin Receptor Involvement in Human Neuroblastoma | 1-gen-2013 | Ruggeri, Pierdomenico; Farina, Antonietta; Cappabianca, LUCIA ANNAMARIA; DI IANNI, Natalia; Ragone, Marzia; Merolle, Stefania; Gulino, A; Mackay, A. R. | |
| TrkAIII promotes microtubule nucleation and assembly at the centrosome in SH-SY5Y neuroblastoma cells, contributing to an undifferentiated anaplastic phenotype. | 1-gen-2013 | Farina, Antonietta; Di Ianni, N; Cappabianca, LUCIA ANNAMARIA; Ruggeri, Pierdomenico; Ragone, M; Ianni, G; Gulino, A; Mackay, ANDREW REAY | |
| Alendronate promotes plasmin-mediated MMP-9 inactivation by exposing cryptic plasmin degradation sites within the MMP-9 catalytic domain. | 1-gen-2012 | Farina, Antonietta; Cappabianca, LUCIA ANNAMARIA; Di Ianni, N; Ruggeri, Pierdomenico; Ragone, M; Merolle, S; Gulino, A; Mackay, ANDREW REAY | |
| Constitutive autotaxin transcription by Nmyc-amplified and non-amplified neuroblastoma cells is regulated by a novel AP-1 and SP-mediated mechanism and abrogated by curcumin | 1-gen-2012 | Farina, Antonietta; Cappabianca, LUCIA ANNAMARIA; Ruggeri, Pierdomenico; Di Ianni, N; Ragone, M; Merolle, S; Sano, K; Stracke, Ml; Horowitz, Jm; Gulino, A; Mackay, ANDREW REAY |