Osteoimmunology is a research field that investigates interactions between bone and immune system. In the light of this new discipline, osteoporosis is acually considered a chronic age-related immune mediated disease. Bone and immune cells are strictly interconnected through a complex network of receptor pathways and cytokines, which in the whole constitute the immunoskeletal interface. Moreover, the cross-talk between immune and bone cells is also involved in the regulation of important body functions beyond bone remodeling and takes part in various pathological conditions sharing an inflammatory background.

Osteoimmunology in aging

GINALDI, Lia;DE MARTINIS, MASSIMO MARIA MARCELLO
2017

Abstract

Osteoimmunology is a research field that investigates interactions between bone and immune system. In the light of this new discipline, osteoporosis is acually considered a chronic age-related immune mediated disease. Bone and immune cells are strictly interconnected through a complex network of receptor pathways and cytokines, which in the whole constitute the immunoskeletal interface. Moreover, the cross-talk between immune and bone cells is also involved in the regulation of important body functions beyond bone remodeling and takes part in various pathological conditions sharing an inflammatory background.
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/11697/110478
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