Continuum Models of Drug Transport to Multiple Cell−Type Population

The principal aim underlying the development of drugs and their administration is to elicit some subcellular level biochemical reaction (often occurring within the cells). Mathematical and pharmacokinetic models have been developed in order to aid researchers by determining the conditions that will control successful delivery of the drug to its target (or the conditions that will limit unintended reactions). Often the models evaluate the transport of the drug at the tissue scale; for example, in order to determine the maximum penetration depth (at some prescribed drug concentration) from the location of administration into poorly vascularized tissue