OBJECT Assessing the modification of protease-protease inhibitory system in ototis media with effusion. MATERIAL AND METHOD The authors closed the eustachian tube in 18 adult rabbits by ligature, coagulation of the tube or by closing one nostril. The middle ear effusion was removed (2 and 10 days after closing the tube or the nostril). RESULTS In the first samples protease activity was higher, while protese inhibitors were lower as compared with the second samples. DISCUSSION The results are in accordance with a modification over time of the effusion characteristics. In the first phase, the proteolytic activity is prevalent. In the absence of a prompt recovery, the excess of antifibrinolytic enzymes let the the process to become chronic.

"Importance of fibrinolytic enzymes on secretory otitis media pathogenesis"

LAURIELLO, MARIA
1987-01-01

Abstract

OBJECT Assessing the modification of protease-protease inhibitory system in ototis media with effusion. MATERIAL AND METHOD The authors closed the eustachian tube in 18 adult rabbits by ligature, coagulation of the tube or by closing one nostril. The middle ear effusion was removed (2 and 10 days after closing the tube or the nostril). RESULTS In the first samples protease activity was higher, while protese inhibitors were lower as compared with the second samples. DISCUSSION The results are in accordance with a modification over time of the effusion characteristics. In the first phase, the proteolytic activity is prevalent. In the absence of a prompt recovery, the excess of antifibrinolytic enzymes let the the process to become chronic.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11697/25350
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