Systemic delivery of drugs by percutaneous permeation (transdermal drug delivery, TDD) offers several advantages compared to oral release or hypodermic injection. Because TDD’s controlled release rate can provide a constant concentration for a long period of time and improved patient compliance, TDD has been shown to be an attractive alternative to oral administration [1]. The most advanced delivery systems (electroporation and cavitational ultrasound) enhance transdermal delivery through a strong and reversible disruption of the stratum corneum (SC), without damaging the deeper tissues.

Transdermal Drug Delivery and Percutaneous Absorption: Mathematical Modeling Perspectives, Chapter 10

DE MONTE, FILIPPO;
2015

Abstract

Systemic delivery of drugs by percutaneous permeation (transdermal drug delivery, TDD) offers several advantages compared to oral release or hypodermic injection. Because TDD’s controlled release rate can provide a constant concentration for a long period of time and improved patient compliance, TDD has been shown to be an attractive alternative to oral administration [1]. The most advanced delivery systems (electroporation and cavitational ultrasound) enhance transdermal delivery through a strong and reversible disruption of the stratum corneum (SC), without damaging the deeper tissues.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11697/26642
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