Psychometric Validation of the Italian Genomic Nursing Concept Inventory: A Cross-Sectional Study Among Nursing Students

Background and Purpose: Genomic literacy is essential for nurses to integrate genomics into clinical practice. The Genomic Nursing Concept Inventory (GNCI) is a validated tool to assess genomic literacy. This study aimed to validate the Italian version of the GNCI (GNCIITA) and evaluate its psychometric properties. Methods: A cross-sectional study was conducted in March 2024 with 315 nursing students from an Italian university. The tool was translated following Beaton’s guidelines, and data were collected via an online survey. Exploratory and confirmatory factor analyses assessed the factor structure. Internal consistency and reliability were evaluated using coefficient α and Spearman–Brown coefficient. Item difficulty and discrimination were also analyzed. Results: The analyses supported a one-factor solution, consistent with the original validation study. Item difficulty and internal consistency of both the full 31-item version and the shortened 20-item version aligned wih the original instrument. Conclusions: The GNCIITA is a reliable instrument for assessing genomic literacy in Italian nursing students.