MALAGRINO', FRANCESCA
MALAGRINO', FRANCESCA
Dipartimento di Medicina clinica, sanità pubblica, scienze della vita e dell'ambiente
The binding selectivity of the C-terminal SH3 domain of Grb2, but not its folding pathway, is dictated by its contiguous SH2 domain
2024-01-01 Di Felice, Mariana; Pagano, Livia; Pennacchietti, Valeria; Diop, Awa; Pietrangeli, Paola; Marcocci, Lucia; Di Matteo, Sara; Malagrino, Francesca; Toto, Angelo; Gianni, Stefano
Exploring the short linear motif-mediated protein-protein interactions of CrkL through ProP-PD
2024-01-01 Via, Pagano; Leandro, Simonetti; Pennacchietti, V.; Toto, A.; Malagrino', Francesca; Ivarsson, Y.; Gianni, Stefano.
The Mechanism of Folding of Human Frataxin in Comparison to the Yeast Homologue – Broad Energy Barriers and the General Properties of the Transition State
2024-01-01 Pietrangeli, Paola; Marcocci, Lucia; Pennacchietti, Valeria; Diop, Awa; Di Felice, Mariana; Pagano, Livia; Malagrino, Francesca; Toto, Angelo; Brunori, Maurizio; Gianni, Stefano
Addressing the Binding Mechanism of the Meprin and TRAF-C Homology Domain of the Speckle-Type POZ Protein Using Protein Engineering
2023-01-01 Diop, Awa; Pietrangeli, Paola; Pennacchietti, Valeria; Pagano, Livia; Toto, Angelo; Di Felice, Mariana; Di Matteo, Sara; Marcocci, Lucia; Malagrino, Francesca; Gianni, Stefano
Characterization of the folding and binding properties of the PTB domain of FRS2 with phosphorylated and unphosphorylated ligands
2023-01-01 Pennacchietti, Valeria; Pagano, Livia; Malagrino, Francesca; Diop, Awa; Di Felice, Mariana; Di Matteo, Sara; Marcocci, Lucia; Pietrangeli, Paola; Toto, Angelo; Gianni, Stefano
Biophysical Characterization of the Binding Mechanism between the MATH Domain of SPOP and Its Physiological Partners
2023-01-01 Diop, Awa; Pietrangeli, Paola; Nardella, Caterina; Pennacchietti, Valeria; Pagano, Livia; Toto, Angelo; Di Felice, Mariana; Di Matteo, Sara; Marcocci, Lucia; Malagrino, Francesca; Gianni, Stefano
Understanding the molecular basis of folding cooperativity through a comparative analysis of a multidomain protein and its isolated domains
2023-01-01 Santorelli, Daniele; Marcocci, Lucia; Pennacchietti, Valeria; Nardella, Caterina; Diop, Awa; Pietrangeli, Paola; Pagano, Livia; Toto, Angelo; Malagrino, Francesca; Gianni, Stefano
An intramolecular energetic network regulates ligand recognition in a SH2 domain
2023-01-01 Nardella, Caterina; Pagano, Livia; Pennacchietti, Valeria; Felice, Mariana Di; Matteo, Sara Di; Diop, Awa; Malagrino, Francesca; Marcocci, Lucia; Pietrangeli, Paola; Gianni, Stefano; Toto, Angelo
Exploring the effect of tethered domains on the folding of Grb2 protein
2022-01-01 Pagano, Livia; Pennacchietti, Valeria; Diop, Awa; Santorelli, Daniele; Pietrangeli, Paola; Marcocci, Lucia; Nardella, Caterina; Malagrino, Francesca; Toto, Angelo; Gianni, Stefano
Characterization of early and late transition states of the folding pathway of a SH2 domain
2022-01-01 Toto, Angelo; Malagrino', Francesca; Nardella, Caterina; Pennacchietti, Valeria; Pagano, Livia; Santorelli, Daniele; Diop, Awa; Gianni, Stefano
Unveiling induced folding of intrinsically disordered proteins – Protein engineering, frustration and emerging themes
2022-01-01 Malagrino', Francesca; Diop, A.; Pagano, L.; Nardella, C.; Toto, A.; Gianni, S.
Cryptic binding properties of a transient folding intermediate in a PDZ tandem repeat
2022-01-01 Malagrino, Francesca; Fusco, Giuliana; Pennacchietti, Valeria; Toto, Angelo; Nardella, Caterina; Pagano, Livia; de Simone, Alfonso; Gianni, Stefano
Folding and Binding Mechanisms of the SH2 Domain from Crkl
2022-01-01 Nardella, Caterina; Toto, Angelo; Santorelli, Daniele; Pagano, Livia; Diop, Awa; Pennacchietti, Valeria; Pietrangeli, Paola; Marcocci, Lucia; Malagrino, Francesca; Gianni, Stefano
On the Effects of Disordered Tails, Supertertiary Structure and Quinary Interactions on the Folding and Function of Protein Domains
2022-01-01 Malagrino', Francesca; Pennacchietti, V.; Santorelli, D.; Pagano, L.; Nardella, C.; Diop, A.; Toto, A.; Gianni, S.
SH2 Domains: Folding, Binding and Therapeutical Approaches
2022-01-01 Diop, Awa; Santorelli, Daniele; Malagrino, Francesca; Nardella, Caterina; Pennacchietti, Valeria; Pagano, Livia; Marcocci, Lucia; Pietrangeli, Paola; Gianni, Stefano; Toto, Angelo
Folding and misfolding of a PDZ tandem repeat
2021-01-01 Visconti, L.; Malagrino, Francesca.; Troilo, F.; Pagano, L.; Toto, A.; Gianni, S.
Experimental characterization of the interaction between the n-terminal sh3 domain of crkl and c3g
2021-01-01 Pagano, L.; Malagrino, Francesca.; Nardella, C.; Gianni, S.; Toto, A.
Double mutant cycles as a tool to address folding, binding, and allostery
2021-01-01 Pagano, L.; Toto, A.; Malagrino', Francesca; Visconti, L.; Jemth, P.; Gianni, S.
Determining folding and binding properties of the C-terminal SH2 domain of SHP2
2021-01-01 Nardella, Caterina; Malagrinò, Francesca; Pagano, Livia; Rinaldo, Serena; Gianni, Stefano; Toto, Angelo
Targeting PDZ domains as potential treatment for viral infections, neurodegeneration and cancer
2021-01-01 Nardella, C.; Visconti, L.; Malagrino, Francesca.; Pagano, L.; Bufano, M.; Nalli, M.; Coluccia, A.; La Regina, G.; Silvestri, R.; Gianni, S.; Toto, A.
Titolo | Data di pubblicazione | Autore(i) | File |
---|---|---|---|
The binding selectivity of the C-terminal SH3 domain of Grb2, but not its folding pathway, is dictated by its contiguous SH2 domain | 1-gen-2024 | Di Felice, Mariana; Pagano, Livia; Pennacchietti, Valeria; Diop, Awa; Pietrangeli, Paola; Marcocci, Lucia; Di Matteo, Sara; Malagrino, Francesca; Toto, Angelo; Gianni, Stefano | |
Exploring the short linear motif-mediated protein-protein interactions of CrkL through ProP-PD | 1-gen-2024 | Via, Pagano; Leandro, Simonetti; Pennacchietti, V.; Toto, A.; Malagrino', Francesca; Ivarsson, Y.; Gianni, Stefano. | |
The Mechanism of Folding of Human Frataxin in Comparison to the Yeast Homologue – Broad Energy Barriers and the General Properties of the Transition State | 1-gen-2024 | Pietrangeli, Paola; Marcocci, Lucia; Pennacchietti, Valeria; Diop, Awa; Di Felice, Mariana; Pagano, Livia; Malagrino, Francesca; Toto, Angelo; Brunori, Maurizio; Gianni, Stefano | |
Addressing the Binding Mechanism of the Meprin and TRAF-C Homology Domain of the Speckle-Type POZ Protein Using Protein Engineering | 1-gen-2023 | Diop, Awa; Pietrangeli, Paola; Pennacchietti, Valeria; Pagano, Livia; Toto, Angelo; Di Felice, Mariana; Di Matteo, Sara; Marcocci, Lucia; Malagrino, Francesca; Gianni, Stefano | |
Characterization of the folding and binding properties of the PTB domain of FRS2 with phosphorylated and unphosphorylated ligands | 1-gen-2023 | Pennacchietti, Valeria; Pagano, Livia; Malagrino, Francesca; Diop, Awa; Di Felice, Mariana; Di Matteo, Sara; Marcocci, Lucia; Pietrangeli, Paola; Toto, Angelo; Gianni, Stefano | |
Biophysical Characterization of the Binding Mechanism between the MATH Domain of SPOP and Its Physiological Partners | 1-gen-2023 | Diop, Awa; Pietrangeli, Paola; Nardella, Caterina; Pennacchietti, Valeria; Pagano, Livia; Toto, Angelo; Di Felice, Mariana; Di Matteo, Sara; Marcocci, Lucia; Malagrino, Francesca; Gianni, Stefano | |
Understanding the molecular basis of folding cooperativity through a comparative analysis of a multidomain protein and its isolated domains | 1-gen-2023 | Santorelli, Daniele; Marcocci, Lucia; Pennacchietti, Valeria; Nardella, Caterina; Diop, Awa; Pietrangeli, Paola; Pagano, Livia; Toto, Angelo; Malagrino, Francesca; Gianni, Stefano | |
An intramolecular energetic network regulates ligand recognition in a SH2 domain | 1-gen-2023 | Nardella, Caterina; Pagano, Livia; Pennacchietti, Valeria; Felice, Mariana Di; Matteo, Sara Di; Diop, Awa; Malagrino, Francesca; Marcocci, Lucia; Pietrangeli, Paola; Gianni, Stefano; Toto, Angelo | |
Exploring the effect of tethered domains on the folding of Grb2 protein | 1-gen-2022 | Pagano, Livia; Pennacchietti, Valeria; Diop, Awa; Santorelli, Daniele; Pietrangeli, Paola; Marcocci, Lucia; Nardella, Caterina; Malagrino, Francesca; Toto, Angelo; Gianni, Stefano | |
Characterization of early and late transition states of the folding pathway of a SH2 domain | 1-gen-2022 | Toto, Angelo; Malagrino', Francesca; Nardella, Caterina; Pennacchietti, Valeria; Pagano, Livia; Santorelli, Daniele; Diop, Awa; Gianni, Stefano | |
Unveiling induced folding of intrinsically disordered proteins – Protein engineering, frustration and emerging themes | 1-gen-2022 | Malagrino', Francesca; Diop, A.; Pagano, L.; Nardella, C.; Toto, A.; Gianni, S. | |
Cryptic binding properties of a transient folding intermediate in a PDZ tandem repeat | 1-gen-2022 | Malagrino, Francesca; Fusco, Giuliana; Pennacchietti, Valeria; Toto, Angelo; Nardella, Caterina; Pagano, Livia; de Simone, Alfonso; Gianni, Stefano | |
Folding and Binding Mechanisms of the SH2 Domain from Crkl | 1-gen-2022 | Nardella, Caterina; Toto, Angelo; Santorelli, Daniele; Pagano, Livia; Diop, Awa; Pennacchietti, Valeria; Pietrangeli, Paola; Marcocci, Lucia; Malagrino, Francesca; Gianni, Stefano | |
On the Effects of Disordered Tails, Supertertiary Structure and Quinary Interactions on the Folding and Function of Protein Domains | 1-gen-2022 | Malagrino', Francesca; Pennacchietti, V.; Santorelli, D.; Pagano, L.; Nardella, C.; Diop, A.; Toto, A.; Gianni, S. | |
SH2 Domains: Folding, Binding and Therapeutical Approaches | 1-gen-2022 | Diop, Awa; Santorelli, Daniele; Malagrino, Francesca; Nardella, Caterina; Pennacchietti, Valeria; Pagano, Livia; Marcocci, Lucia; Pietrangeli, Paola; Gianni, Stefano; Toto, Angelo | |
Folding and misfolding of a PDZ tandem repeat | 1-gen-2021 | Visconti, L.; Malagrino, Francesca.; Troilo, F.; Pagano, L.; Toto, A.; Gianni, S. | |
Experimental characterization of the interaction between the n-terminal sh3 domain of crkl and c3g | 1-gen-2021 | Pagano, L.; Malagrino, Francesca.; Nardella, C.; Gianni, S.; Toto, A. | |
Double mutant cycles as a tool to address folding, binding, and allostery | 1-gen-2021 | Pagano, L.; Toto, A.; Malagrino', Francesca; Visconti, L.; Jemth, P.; Gianni, S. | |
Determining folding and binding properties of the C-terminal SH2 domain of SHP2 | 1-gen-2021 | Nardella, Caterina; Malagrinò, Francesca; Pagano, Livia; Rinaldo, Serena; Gianni, Stefano; Toto, Angelo | |
Targeting PDZ domains as potential treatment for viral infections, neurodegeneration and cancer | 1-gen-2021 | Nardella, C.; Visconti, L.; Malagrino, Francesca.; Pagano, L.; Bufano, M.; Nalli, M.; Coluccia, A.; La Regina, G.; Silvestri, R.; Gianni, S.; Toto, A. |