MACKAY, ANDREW REAY
MACKAY, ANDREW REAY
Dipartimento di Scienze cliniche applicate e biotecnologiche
A Study of Alternative TrkA Splicing Identifies TrkAIII as a Novel Potentially Targetable Participant in PitNET Progression
2024-01-01 Sbaffone, M.; Jaffrain-Rea, M. -L.; Cappabianca, L.; Carbonara, F.; Gianno, F.; Feola, T.; Ruggieri, M.; Zelli, V.; Maccarone, R.; Guadagni, S.; Clementi, M.; Arcella, A.; Esposito, V.; Carozza, G.; Martelli, I.; Farina, A. R.; Mackay, A. R.
Molecular Characterization and Inhibition of a Novel Stress-Induced Mitochondrial Protecting Role for Misfolded TrkAIII in Human SH-SY5Y Neuroblastoma Cells
2024-01-01 Cappabianca, Lucia; Ruggieri, Marianna; Sebastiano, Michela; Sbaffone, Maddalena; Martelli, Ilaria; Ruggeri, Pierdomenico; DI PADOVA, Monica; Farina, Antonietta; Mackay, ANDREW REAY
Studies on potentially druggable pathways that regulate stress-induced TrkAIII mitochondrial internalization, cleavage and activation in human neuroblastoma cells
2023-01-01 Ruggieri, M.; Cappabianca, L.; Sbaffone, M.; Martelli, I.; Farina, A. R.; Mackay, A. R.
The TrkAIII splice variant oncoprotein enhances PD-L1 expression in human SH-SY5Y neuroblastoma cells
2023-01-01 Sbaffone, M.; Cappabianca, L.; Ruggieri, M.; Zelli, V.; Martelli, I.; Farina, A. R.; Mackay, A. R.
The Alternative TrkAIII Splice Variant, a Targetable Oncogenic Participant in Human Cutaneous Malignant Melanoma
2023-01-01 Cappabianca, Lucia; Zelli, Veronica; Pellegrini, Cristina; Sebastiano, Michela; Maccarone, Rita; Clementi, Marco; Chiominto, Alessandro; Ruggeri, Pierdomenico; Cardelli, Ludovica; Ruggieri, Marianna; Sbaffone, Maddalena; Fargnoli, Maria-Concetta; Guadagni, Stefano; Farina, Antonietta R.; Mackay, Andrew R.
Hypoxia-induced alternative TrkA splicing and reoxygenation-dependent TrkAIII activation: A cycling hypoxia-regulated resistance mechanism in neuroblastoma.
2022-01-01 Cappabianca, Lucia; Farina, Antonietta; Sebastiano, Michela; Ruggieri, Marianna; Sbaffone, Maddalena; Mackay, ANDREW REAY
Nutraceutical Preventative and Therapeutic Potential in Neuroblastoma: From Pregnancy to Early Childhood
2022-01-01 Sbaffone, Maddalena; Ruggieri, Marianna; Sebastiano, Michela; Mackay, Andrew Reay; Zelli, Veronica; Farina, Antonietta Rosella; Cappabianca, Lucia Annamaria
Circulating tumour cell gene expression and chemosensitivity analyses: predictive accuracy for response to multidisciplinary treatment of patients with unresectable refractory recurrent rectal cancer or unresectable refractory colorectal cancer liver metastases
2022-01-01 Guadagni, Stefano; Masedu, Francesco; Fiorentini, Giammaria; Sarti, Donatella; Fiorentini, Caterina; Guadagni, Veronica; Apostolou, Panagiotis; Papasotiriou, Ioannis; Parsonidis, Panagiotis; Valenti, Marco; Ricevuto, Enrico; Bruera, Gemma; Farina, Antonietta R; Mackay, Andrew R; Clementi, Marco
Doxorubicin-Induced TrkAIII Activation: A Selection Mechanism for Resistant Dormant Neuroblastoma Cells
2022-01-01 Cappabianca, Lucia; Sebastiano, Michela; Ruggieri, Marianna; Sbaffone, Maddalena; Zelli, Veronica; Farina, Antonietta Rosella; Mackay, Andrew Reay
Mechanisms involved in selecting and maintaining neuroblastoma cancer stem cell populations, and perspectives for therapeutic targeting
2021-01-01 Farina, A. R.; Cappabianca, L. A.; Zelli, V.; Sebastiano, M.; Mackay, A. R.
A Prospective Study of Intraarterial Infusion Chemotherapy in Advanced WT BRAF Melanoma Patients
2021-01-01 Guadagni, S.; Zoras, O.; Fiorentini, G.; Masedu, F.; Lasithiotakis, K.; Sarti, D.; Farina, A. R.; Mackay, A. R.; Clementi, M.
Precision oncotherapy based on liquid biopsies in multidisciplinary treatment of unresectable recurrent rectal cancer: a retrospective cohort study
2020-01-01 Guadagni, Stefano; Fiorentini, Giammaria; De Simone, Michele; Masedu, Francesco; Zoras, Odisseas; Mackay, Andrew Reay; Sarti, Donatella; Papasotiriou, Ioannis; Apostolou, Panagiotis; Catarci, Marco; Clementi, Marco; Ricevuto, Enrico; Bruera, Gemma
A Pilot Study of the Predictive Potential of Chemosensitivity and Gene Expression Assays Using Circulating Tumour Cells from Patients with Recurrent Ovarian Cancer
2020-01-01 Guadagni, S.; Clementi, M.; Masedu, F.; Fiorentini, G.; Sarti, D.; Deraco, M.; Kusamura, S.; Papasotiriou, I.; Apostolou, P.; Aigner, K. R.; Zavattieri, G.; Farina, A. R.; Vizzielli, G.; Scambia, G.; Mackay, A. R.
Real-life multidisciplinary treatment for unresectable colorectal cancer liver metastases including hepatic artery infusion with chemo-filtration and liquid biopsy precision oncotherapy: observational cohort study
2020-01-01 Guadagni, S.; Clementi, M.; Mackay, A. R.; Ricevuto, E.; Fiorentini, G.; Sarti, D.; Palumbo, P.; Apostolou, P.; Papasotiriou, I.; Masedu, F.; Valenti, M.; Giordano, A. V.; Bruera, G.
Multidisciplinary Treatment, Including Locoregional Chemotherapy, for Merkel-Polyomavirus-Positive Merkel Cell Carcinomas: Perspectives for Patients Exhibiting Oncogenic Alternative Δ exon 6–7 TrkAIII Splicing of Neurotrophin Receptor Tropomyosin-Related Kinase A
2020-01-01 Guadagni, Stefano; Farina, Antonietta; Cappabianca, LUCIA ANNA MARIA; Sebastiano, Michela; Maccarone, Rita; Zelli, Veronica; Clementi, Marco; Chiominto, Alessandro; Bruera, Gemma; Ricevuto, Enrico; Fiorentini, Giammaria; Sarti, Donatella; Mackay, ANDREW REAY
Circulating tumour cell liquid biopsy in selecting therapy for recurrent cutaneous melanoma with locoregional pelvic metastases: A pilot study
2020-01-01 Guadagni, S.; Fiorentini, G.; Papasotiriou, I.; Apostolou, P.; Masedu, F.; Sarti, D.; Farina, A. R.; Mackay, A. R.; Clementi, M.
Immune response activation following hyperthermic intraperitoneal chemotherapy for peritoneal metastases: A pilot study
2020-01-01 Fiorentini, G; Sarti, D; Patriti, A; Eugeni, E; Guerra, F; Masedu, F; Mackay, Ar; Guadagni, S
Successful laparoscopic trans-peritoneal repair of an incisional inguinal hernia, resulting from deep lymph node dissection for melanoma: A case report
2020-01-01 Clementi, M.; Di Furia, M.; Sista, F.; Mackay, A. R.; Guadagni, S.
Hypoxia-induced alternative splicing: the 11th Hallmark of Cancer
2020-01-01 Farina, A. R.; Cappabianca, L.; Sebastiano, M.; Zelli, V.; Guadagni, S.; Mackay, A. R.
Multidisciplinary palliation for unresectable recurrent rectal cancer: Hypoxic pelvic perfusion with mitomycin C and oxaliplatin in patients progressing after systemic chemotherapy and radiotherapy, a retrospective cohort study
2019-01-01 Guadagni, S.; Fiorentini, G.; Mambrini, A.; Masedu, F.; Valenti, M.; Mackay, A. R.; Sarti, D.; Ricevuto, E.; Clementi, M.; Catarci, M.; Lazzarin, Gianni; Bruera, G.
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| A Study of Alternative TrkA Splicing Identifies TrkAIII as a Novel Potentially Targetable Participant in PitNET Progression | 1-gen-2024 | Sbaffone, M.; Jaffrain-Rea, M. -L.; Cappabianca, L.; Carbonara, F.; Gianno, F.; Feola, T.; Ruggieri, M.; Zelli, V.; Maccarone, R.; Guadagni, S.; Clementi, M.; Arcella, A.; Esposito, V.; Carozza, G.; Martelli, I.; Farina, A. R.; Mackay, A. R. | |
| Molecular Characterization and Inhibition of a Novel Stress-Induced Mitochondrial Protecting Role for Misfolded TrkAIII in Human SH-SY5Y Neuroblastoma Cells | 1-gen-2024 | Cappabianca, Lucia; Ruggieri, Marianna; Sebastiano, Michela; Sbaffone, Maddalena; Martelli, Ilaria; Ruggeri, Pierdomenico; DI PADOVA, Monica; Farina, Antonietta; Mackay, ANDREW REAY | |
| Studies on potentially druggable pathways that regulate stress-induced TrkAIII mitochondrial internalization, cleavage and activation in human neuroblastoma cells | 1-gen-2023 | Ruggieri, M.; Cappabianca, L.; Sbaffone, M.; Martelli, I.; Farina, A. R.; Mackay, A. R. | |
| The TrkAIII splice variant oncoprotein enhances PD-L1 expression in human SH-SY5Y neuroblastoma cells | 1-gen-2023 | Sbaffone, M.; Cappabianca, L.; Ruggieri, M.; Zelli, V.; Martelli, I.; Farina, A. R.; Mackay, A. R. | |
| The Alternative TrkAIII Splice Variant, a Targetable Oncogenic Participant in Human Cutaneous Malignant Melanoma | 1-gen-2023 | Cappabianca, Lucia; Zelli, Veronica; Pellegrini, Cristina; Sebastiano, Michela; Maccarone, Rita; Clementi, Marco; Chiominto, Alessandro; Ruggeri, Pierdomenico; Cardelli, Ludovica; Ruggieri, Marianna; Sbaffone, Maddalena; Fargnoli, Maria-Concetta; Guadagni, Stefano; Farina, Antonietta R.; Mackay, Andrew R. | |
| Hypoxia-induced alternative TrkA splicing and reoxygenation-dependent TrkAIII activation: A cycling hypoxia-regulated resistance mechanism in neuroblastoma. | 1-gen-2022 | Cappabianca, Lucia; Farina, Antonietta; Sebastiano, Michela; Ruggieri, Marianna; Sbaffone, Maddalena; Mackay, ANDREW REAY | |
| Nutraceutical Preventative and Therapeutic Potential in Neuroblastoma: From Pregnancy to Early Childhood | 1-gen-2022 | Sbaffone, Maddalena; Ruggieri, Marianna; Sebastiano, Michela; Mackay, Andrew Reay; Zelli, Veronica; Farina, Antonietta Rosella; Cappabianca, Lucia Annamaria | |
| Circulating tumour cell gene expression and chemosensitivity analyses: predictive accuracy for response to multidisciplinary treatment of patients with unresectable refractory recurrent rectal cancer or unresectable refractory colorectal cancer liver metastases | 1-gen-2022 | Guadagni, Stefano; Masedu, Francesco; Fiorentini, Giammaria; Sarti, Donatella; Fiorentini, Caterina; Guadagni, Veronica; Apostolou, Panagiotis; Papasotiriou, Ioannis; Parsonidis, Panagiotis; Valenti, Marco; Ricevuto, Enrico; Bruera, Gemma; Farina, Antonietta R; Mackay, Andrew R; Clementi, Marco | |
| Doxorubicin-Induced TrkAIII Activation: A Selection Mechanism for Resistant Dormant Neuroblastoma Cells | 1-gen-2022 | Cappabianca, Lucia; Sebastiano, Michela; Ruggieri, Marianna; Sbaffone, Maddalena; Zelli, Veronica; Farina, Antonietta Rosella; Mackay, Andrew Reay | |
| Mechanisms involved in selecting and maintaining neuroblastoma cancer stem cell populations, and perspectives for therapeutic targeting | 1-gen-2021 | Farina, A. R.; Cappabianca, L. A.; Zelli, V.; Sebastiano, M.; Mackay, A. R. | |
| A Prospective Study of Intraarterial Infusion Chemotherapy in Advanced WT BRAF Melanoma Patients | 1-gen-2021 | Guadagni, S.; Zoras, O.; Fiorentini, G.; Masedu, F.; Lasithiotakis, K.; Sarti, D.; Farina, A. R.; Mackay, A. R.; Clementi, M. | |
| Precision oncotherapy based on liquid biopsies in multidisciplinary treatment of unresectable recurrent rectal cancer: a retrospective cohort study | 1-gen-2020 | Guadagni, Stefano; Fiorentini, Giammaria; De Simone, Michele; Masedu, Francesco; Zoras, Odisseas; Mackay, Andrew Reay; Sarti, Donatella; Papasotiriou, Ioannis; Apostolou, Panagiotis; Catarci, Marco; Clementi, Marco; Ricevuto, Enrico; Bruera, Gemma | |
| A Pilot Study of the Predictive Potential of Chemosensitivity and Gene Expression Assays Using Circulating Tumour Cells from Patients with Recurrent Ovarian Cancer | 1-gen-2020 | Guadagni, S.; Clementi, M.; Masedu, F.; Fiorentini, G.; Sarti, D.; Deraco, M.; Kusamura, S.; Papasotiriou, I.; Apostolou, P.; Aigner, K. R.; Zavattieri, G.; Farina, A. R.; Vizzielli, G.; Scambia, G.; Mackay, A. R. | |
| Real-life multidisciplinary treatment for unresectable colorectal cancer liver metastases including hepatic artery infusion with chemo-filtration and liquid biopsy precision oncotherapy: observational cohort study | 1-gen-2020 | Guadagni, S.; Clementi, M.; Mackay, A. R.; Ricevuto, E.; Fiorentini, G.; Sarti, D.; Palumbo, P.; Apostolou, P.; Papasotiriou, I.; Masedu, F.; Valenti, M.; Giordano, A. V.; Bruera, G. | |
| Multidisciplinary Treatment, Including Locoregional Chemotherapy, for Merkel-Polyomavirus-Positive Merkel Cell Carcinomas: Perspectives for Patients Exhibiting Oncogenic Alternative Δ exon 6–7 TrkAIII Splicing of Neurotrophin Receptor Tropomyosin-Related Kinase A | 1-gen-2020 | Guadagni, Stefano; Farina, Antonietta; Cappabianca, LUCIA ANNA MARIA; Sebastiano, Michela; Maccarone, Rita; Zelli, Veronica; Clementi, Marco; Chiominto, Alessandro; Bruera, Gemma; Ricevuto, Enrico; Fiorentini, Giammaria; Sarti, Donatella; Mackay, ANDREW REAY | |
| Circulating tumour cell liquid biopsy in selecting therapy for recurrent cutaneous melanoma with locoregional pelvic metastases: A pilot study | 1-gen-2020 | Guadagni, S.; Fiorentini, G.; Papasotiriou, I.; Apostolou, P.; Masedu, F.; Sarti, D.; Farina, A. R.; Mackay, A. R.; Clementi, M. | |
| Immune response activation following hyperthermic intraperitoneal chemotherapy for peritoneal metastases: A pilot study | 1-gen-2020 | Fiorentini, G; Sarti, D; Patriti, A; Eugeni, E; Guerra, F; Masedu, F; Mackay, Ar; Guadagni, S | |
| Successful laparoscopic trans-peritoneal repair of an incisional inguinal hernia, resulting from deep lymph node dissection for melanoma: A case report | 1-gen-2020 | Clementi, M.; Di Furia, M.; Sista, F.; Mackay, A. R.; Guadagni, S. | |
| Hypoxia-induced alternative splicing: the 11th Hallmark of Cancer | 1-gen-2020 | Farina, A. R.; Cappabianca, L.; Sebastiano, M.; Zelli, V.; Guadagni, S.; Mackay, A. R. | |
| Multidisciplinary palliation for unresectable recurrent rectal cancer: Hypoxic pelvic perfusion with mitomycin C and oxaliplatin in patients progressing after systemic chemotherapy and radiotherapy, a retrospective cohort study | 1-gen-2019 | Guadagni, S.; Fiorentini, G.; Mambrini, A.; Masedu, F.; Valenti, M.; Mackay, A. R.; Sarti, D.; Ricevuto, E.; Clementi, M.; Catarci, M.; Lazzarin, Gianni; Bruera, G. |