IRIS
MACKAY, ANDREW REAY
 Distribuzione geografica
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Continente #
NA - Nord America 2.770
EU - Europa 1.602
AS - Asia 768
Continente sconosciuto - Info sul continente non disponibili 8
OC - Oceania 6
AF - Africa 2
SA - Sud America 2
Totale 5.158
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Nazione #
US - Stati Uniti d'America 2.768
IE - Irlanda 616
CN - Cina 420
TR - Turchia 289
IT - Italia 189
DE - Germania 175
SE - Svezia 169
UA - Ucraina 158
GB - Regno Unito 133
FI - Finlandia 78
FR - Francia 53
IN - India 22
VN - Vietnam 22
BE - Belgio 18
EU - Europa 8
KR - Corea 8
RU - Federazione Russa 5
AU - Australia 3
IL - Israele 3
NZ - Nuova Zelanda 3
BR - Brasile 2
CA - Canada 2
ES - Italia 2
HK - Hong Kong 2
NL - Olanda 2
CH - Svizzera 1
EG - Egitto 1
GR - Grecia 1
ID - Indonesia 1
NG - Nigeria 1
PT - Portogallo 1
SK - Slovacchia (Repubblica Slovacca) 1
TH - Thailandia 1
Totale 5.158
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Città #
Chandler 659
Jacksonville 647
Dublin 616
Izmir 133
Nanjing 121
Wilmington 115
San Mateo 99
Boardman 96
New York 93
Lawrence 85
Princeton 85
Ashburn 80
Beijing 58
Ann Arbor 54
Dearborn 53
Nanchang 48
L'aquila 46
Milan 37
Shenyang 37
Verona 26
Mountain View 25
Seattle 25
Tianjin 25
Des Moines 22
Dong Ket 22
Falls Church 20
Bremen 17
Brussels 17
Hebei 17
Woodbridge 15
Philadelphia 14
Impruneta 13
Guangzhou 11
Jinan 11
Kunming 11
Jiaxing 10
Helsinki 9
Norwalk 9
Washington 9
Ningbo 8
Taizhou 8
Changsha 7
Shanghai 7
Zhengzhou 7
Auburn Hills 6
Changchun 6
Hefei 6
Los Angeles 6
West Jordan 6
Hangzhou 5
Pune 5
Cambridge 4
Houston 4
Lanzhou 4
San Francisco 4
Strasbourg 4
Bologna 3
Catania 3
Düsseldorf 3
Haikou 3
L’Aquila 3
Redwood City 3
Rome 3
Trieste 3
Altidona 2
Auckland 2
Borås 2
Cava de' Tirreni 2
Cedar Knolls 2
Central 2
Cesena 2
Chieti 2
Fairfield 2
Ferentino 2
Fremont 2
Lanciano 2
Sora 2
Taiyuan 2
Tappahannock 2
Trestina 2
Alzira 1
Amsterdam 1
Aquila 1
Athens 1
Aversa 1
Bangkok 1
Berlin 1
Bratislava 1
Campobasso 1
Canberra 1
Charlotte 1
Chongqing 1
Cleveland 1
Frosinone 1
Fuzhou 1
Gent 1
Hanover 1
Jakarta 1
Kadima Zoran 1
Kerkrade 1
Totale 3.663
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Nome #
Gelatinase B/MMP-9 in Tumour Pathogenesis and Progression. 99
TrkAIII signals endoplasmic reticulum stress to the mitochondria in neuroblastoma cells, resulting in glycolytic metabolic adaptation 94
The neuroblastoma tumour-suppressor TrkAI and its oncogenic alternative TrkAIII splice variant exhibit geldanamycin-sensitive interactions with Hsp90 in human neuroblastoma cells 94
NGF sensitizes TrkA SH-SY5Y neuroblastoma cells to TRAIL-induced apoptosis 93
TRAIL induces pro-apoptotic crosstalk between the TRAIL-receptor signaling pathway and TRKIII in SH-SY5Y cells, unveiling a potential therapeutic “Achilles heel” for the TrkAIII oncoprotein in neuroblastoma 91
Transcriptional regulation of intercellular adhesion molecule 1 by phorbol ester in human neuroblastoma cell line SK-N-SH involves jun- and fos-containing activator protein 1 site binding complex(es) 85
Alternative TrkAIII splicing: a potential regulated tumor-promoting switch and therapeutic target in Neuroblastoma 80
EGF- and cell-cycle-regulated STAG1/PMEPA1 ERG1.2 belongs to a conserved gene family and is overexpressed and amplified in breast and ovarian cancer 78
Transcriptional up-regulation of matrix metalloproteinase-9 expression during spontaneous epithelial to neuroblast phenotype conversion by SK-N-SH neuroblastoma cells, involved in enhanced invasivity, depends upon GT-box and nuclear factor kappa B elements 78
All-trans-retinoic acid induces nuclear factor kappa B activation and matrix metalloproteinase-9 expression and enhances basement membrane invasivity of differentiation-resistant human SK-N-BE 9N neuroblastoma cells 76
TrkA alternative splicing: A regulated tumor-promoting switch in human neuroblastoma 75
Thioredoxin alters the matrix metalloproteinase/tissue inhibitors of metalloproteinase balance and stimulates human SK-N-SH neuroblastoma cell invasion 75
Retrograde TrkAIII transport from ERGIC to ER: a re-localisation mechanism for oncogenic activity 74
Cis Golgi network-associated TrkAIII targets the interphase centrosome and promotes genetic instability 73
Constitutive autotaxin transcription by Nmyc-amplified and non-amplified neuroblastoma cells is regulated by a novel AP-1 and SP-mediated mechanism and abrogated by curcumin 72
Pyrrolopyrimidine c-Src inhibitors reduce growth, adhesion, motility and invasion of prostate cancer cells in vitro 70
Activation of MMP-2 by human GCT23 giant cell tumour cells induced by osteopontin, bone sialoprotein and GRGDSP peptides is RGD and cell shape change dependent 69
The effect of GRGDSP peptide, osteopontin and bone sialoprotein on metalloproteinases, tissue inhibitors of metalloproteinases, and plasminogen activators secreted by human osteoclastoma cells. 68
DIFFERENTIAL EXPRESSION OF TUMOR-CELL METALLOPROTEINASES AND TIMPS BY A PHORBOL ESTER 68
The TrkAIII oncoprotein inhibits mitochondrial free radical ROS-induced death of SH-SY5Y neuroblastoma cells by augmenting SOD2 expression and activity at the mitochondria, within the context of a tumour stem cell-like phenotype. 68
TrkAIII promotes microtubule nucleation and assembly at the centrosome in SH-SY5Y neuroblastoma cells, contributing to an undifferentiated anaplastic phenotype. 67
The enemy from within: Miss-localization of a compromised receptor as a mechanism for TrkAIII oncogenic activity 67
Real-life multidisciplinary treatment for unresectable colorectal cancer liver metastases including hepatic artery infusion with chemo-filtration and liquid biopsy precision oncotherapy: observational cohort study 66
FOLLICLE-STIMULATING HORMONE INCREASES THE EXPRESSION OF TISSUE INHIBITORS OF METALLOPROTEINASES TIMP-1 AND TIMP-2 AND INDUCES TIMP-1 AP-1 SITE BINDING COMPLEX(ES) IN PREPUBERTAL RAT SERTOLI CELLS 65
Mode of formation of synovial villi 64
TrkAIII expression in the thymus 64
Thioredoxin stimulates MMP-9 expression, de-regulates the MMP-9/TIMP-1 equilibrium and promotes MMP-9 dependent invasion in human MDA-MB-231 breast cancer cells. 63
MAPPING OF RECEPTOR-BINDING SITES ON IL-1-BETA BY RECONSTRUCTION OF IL-1RA-LIKE DOMAINS 63
Alternative TrkA splicing and neuroblastoma 63
Inhibition of human MDA-MB-231 breast cancer cell invasion by matrix metalloproteinase 3 involves degradation of plasminogen 63
NGF FLIPs TrkA onto the death TRAIL in neuroblastoma cells 63
TRAIL induces pro-apoptotic crosstalk between the TRAIL-receptor signaling pathway and TrkAIII in SH-SY5Y cells 63
RAS LEVELS AND METALLOPROTEINASE ACTIVITY IN NORMAL VERSUS NEOPLASTIC RAT MAMMARY TISSUES 62
Increased chemiluminescence of polymorphonuclear leucocytes from patients with progressive systemic sclerosis 62
Alternative TrkAIII splicing and Cancer 62
Characterisation of metastatic tumour cells 62
Nifedipine in the treatment of Raynaud's phenomenon in patients with systemic sclerosis 62
Effect of phorbol ester and cytokines on matrix metalloproteinase and tissue inhibitor of metalloproteinase expression in tumor and normal cell lines. 61
STUDIES ON THE EFFECTS OF LAMININ, E-8 FRAGMENT OF LAMININ AND SYNTHETIC LAMININ PEPTIDES PA22-2 AND YIGSR ON MATRIX METALLOPROTEINASES AND TISSUE INHIBITOR OF METALLOPROTEINASE EXPRESSION 61
The oncogenic neurotrophin receptor tropomyosin-related kinase variant, TrkAIII 61
Alendronate promotes plasmin-mediated MMP-9 inactivation by exposing cryptic plasmin degradation sites within the MMP-9 catalytic domain. 61
Tyrosine kinase Src inhibitors: Cellular mechanisms for potential therapeutic applications in bone disease. 60
Neurotrophin and Neurotrophin Receptor Involvement in Human Neuroblastoma 60
Opposing roles for specific TIMPs in breast cancer prognostic 59
BASEMENT-MEMBRANE TYPE-IV COLLAGEN DEGRADATION - EVIDENCE FOR THE INVOLVEMENT OF A PROTEOLYTIC CASCADE INDEPENDENT OF METALLOPROTEINASES 59
Effect of a lymphocyte-derived pro-inflammatory factor on carrageenan pleurisy in the rat 59
The transition from acute to chronic inflammation 59
Identification of plasminogen in Matrigel(TM) and its activation by reconstitution of this basement membrane extract 58
Precision oncotherapy based on liquid biopsies in multidisciplinary treatment of unresectable recurrent rectal cancer: a retrospective cohort study 58
A pilot study of alternative TrkAIII splicing in Merkel cell carcinoma: a potential oncogenic mechanism and novel therapeutic target 58
IDENTIFICATION OF THE 72-KDA (MMP-2) AND 92-KDA (MMP-9) GELATINASE TYPE-IV COLLAGENASE IN PREPARATIONS OF LAMININ AND MATRIGEL(TM) 57
Alternative TrkA splicing and Cancer 56
REN: a novel, developmentally regulated gene that promotes neural cell differentiation 56
EXPRESSION OF 72 KD GELATINASE AND TYPE-IV COLLAGEN DURING CARBON TETRACHLORIDE-INDUCED RAT-LIVER FIBROSIS 55
Studies into the mode of action of non-steroidal anti-inflammatory drugs using a model of facsimile synovium 55
The effects of levan on the acute inflammatory response 54
TrkAIII: A Novel Hypoxia-regulated Alternative TrkA Splice Variant of Potential Physiological and Pathological Importance 54
Multidisciplinary palliation for unresectable recurrent rectal cancer: Hypoxic pelvic perfusion with mitomycin C and oxaliplatin in patients progressing after systemic chemotherapy and radiotherapy, a retrospective cohort study 54
bc1-2 over-expression enhances NF-kappa B activity and induces mmp-9 transcription in human MCF7(ADR) breast-cancer cells 53
TRKAIII COMMUNICATES ER-STRESS TO THE MITO-CHONDRIA IN NEUROBLASTOMA CELLS, RESULTING INGLYCOLYTIC METABOLIC ADAPTATION 53
The interaction of leucocytes with vascular endothelial cells in vitro with respect to experimental inflammation in the rat 52
Thioredoxin inhibits microvascular endothelial capillary tubule formation 51
Reconstitution of TIMP-2 expression in SH-SY5Y neuroblastoma cells by 5-azacytidine is mediated transcriptionally by NF-Y through an inverted CCAAT site 49
Enhancement of colloidal clearance in normal rats by sodium diethyl dithiocarbamate (DTC) 49
STUDIES ON THE ABILITY OF 65-KDA AND 92-KDA TUMOR-CELL GELATINASES TO DEGRADE TYPE-IV COLLAGEN 49
Successful laparoscopic trans-peritoneal repair of an incisional inguinal hernia, resulting from deep lymph node dissection for melanoma: A case report 48
Tissue inhibitor of metalloproteinase-2 protection of matrix metalloproteinase-2 from degradation by plasmin is reversed by divalent cation chelator EDTA and the bisphosphonate alendronate 47
The alternative TrkAIII splice variant expressed by human neuroblastomas and glioblastomas targets the centrosome and promotes genetic instability 47
Effect of acute acupuncture on acute inflammation 47
Multidisciplinary Treatment, Including Locoregional Chemotherapy, for Merkel-Polyomavirus-Positive Merkel Cell Carcinomas: Perspectives for Patients Exhibiting Oncogenic Alternative Δ exon 6–7 TrkAIII Splicing of Neurotrophin Receptor Tropomyosin-Related Kinase A 47
The alternative TRKAIII splice variant targets the centrosome and promotes genetic instability 46
Advanced Merkel cell carcinoma of the lower extremity treated with surgery and isolated pelvic and limb perfusion using Melphalan: A case of unexpected long-term survival 46
Discovery, characterization and potential roles of a novel NF-YAx splice variant in human neuroblastoma 45
Isolation and characterization of human natural killer cells 44
Circulating tumour cell liquid biopsy in selecting therapy for recurrent cutaneous melanoma with locoregional pelvic metastases: A pilot study 44
RETINOIC ACID-ENHANCED INVASION THROUGH RECONSTITUTED BASEMENT MEMBRANE BY HUMAN SK-N-SH NEUROBLASTOMA CELLS INVOLVES MEMBRANE-ASSACIATED TISSUE-TYPE PLASMINOGEN ACTIVATOR 43
Pyrrolopyrimidine class Src inhibitors inhibit osteoclast and bone metastatic tumor cell functions. 43
The role of plasma factors in the adherence of leucocytes to vascular endothelial cells 43
A Prospective Study of Intraarterial Infusion Chemotherapy in Advanced WT BRAF Melanoma Patients 43
Circulating tumour cell gene expression and chemosensitivity analyses: predictive accuracy for response to multidisciplinary treatment of patients with unresectable refractory recurrent rectal cancer or unresectable refractory colorectal cancer liver metastases 41
null 39
Spontaneous metastasis of rat liver epithelial cells transformed with v-raf and v-raf/v-myc: association with different phenotypic properties 38
Hypoxia-induced alternative splicing: the 11th Hallmark of Cancer 38
A Pilot Study of the Predictive Potential of Chemosensitivity and Gene Expression Assays Using Circulating Tumour Cells from Patients with Recurrent Ovarian Cancer 38
null 35
The Alternative TrkAIII Splice Variant, a Targetable Oncogenic Participant in Human Cutaneous Malignant Melanoma 33
Mechanisms involved in selecting and maintaining neuroblastoma cancer stem cell populations, and perspectives for therapeutic targeting 32
Immune response activation following hyperthermic intraperitoneal chemotherapy for peritoneal metastases: A pilot study 31
Doxorubicin-Induced TrkAIII Activation: A Selection Mechanism for Resistant Dormant Neuroblastoma Cells 31
NGF sensitizes TrKA expressing SH-SY5Y nuroblastoma cells to TRAIL-induced apoptosisi 28
NGF Sensitizes TrkA SH-SY5Y Neuroblastoma Cells to TRAIL-Induced Apoptosis 26
Nutraceutical Preventative and Therapeutic Potential in Neuroblastoma: From Pregnancy to Early Childhood 19
The TrkAIII splice variant oncoprotein enhances PD-L1 expression in human SH-SY5Y neuroblastoma cells 4
Studies on potentially druggable pathways that regulate stress-induced TrkAIII mitochondrial internalization, cleavage and activation in human neuroblastoma cells 4
Hypoxia-induced alternative TrkA splicing and reoxygenation-dependent TrkAIII activation: A cycling hypoxia-regulated resistance mechanism in neuroblastoma. 3
A Study of Alternative TrkA Splicing Identifies TrkAIII as a Novel Potentially Targetable Participant in PitNET Progression 1
Totale 5.306
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Categoria #
all - tutte 18.278
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 18.278
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2018/2019221 0 0 0 0 0 0 0 0 0 10 11 200
2019/2020755 137 0 82 7 16 105 158 28 96 32 11 83
2020/2021693 13 84 2 86 97 16 92 10 88 20 147 38
2021/2022503 35 41 59 23 40 13 13 34 28 11 40 166
2022/20231.812 125 115 39 191 172 206 3 102 775 11 40 33
2023/2024386 61 25 44 46 35 139 1 22 5 8 0 0
Totale 5.306