IRIS
MACKAY, ANDREW REAY
 Distribuzione geografica
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Continente #
NA - Nord America 4.144
AS - Asia 2.355
EU - Europa 2.266
SA - Sud America 340
AF - Africa 36
Continente sconosciuto - Info sul continente non disponibili 9
OC - Oceania 6
Totale 9.156
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Nazione #
US - Stati Uniti d'America 4.083
SG - Singapore 982
IE - Irlanda 609
CN - Cina 595
DE - Germania 311
TR - Turchia 303
BR - Brasile 295
HK - Hong Kong 251
IT - Italia 251
RU - Federazione Russa 236
SE - Svezia 180
GB - Regno Unito 173
UA - Ucraina 163
FI - Finlandia 130
VN - Vietnam 80
FR - Francia 61
IN - India 47
CA - Canada 32
CZ - Repubblica Ceca 32
BE - Belgio 21
PL - Polonia 20
ES - Italia 19
AT - Austria 18
MX - Messico 18
JP - Giappone 17
AR - Argentina 16
ZA - Sudafrica 16
BD - Bangladesh 13
NL - Olanda 11
KR - Corea 9
EC - Ecuador 8
EU - Europa 8
IQ - Iraq 8
LT - Lituania 8
UY - Uruguay 7
UZ - Uzbekistan 7
AE - Emirati Arabi Uniti 6
ID - Indonesia 5
MA - Marocco 5
PK - Pakistan 5
EG - Egitto 4
IL - Israele 4
KZ - Kazakistan 4
VE - Venezuela 4
AU - Australia 3
BH - Bahrain 3
BY - Bielorussia 3
DZ - Algeria 3
NZ - Nuova Zelanda 3
PA - Panama 3
PT - Portogallo 3
AL - Albania 2
BA - Bosnia-Erzegovina 2
CH - Svizzera 2
CL - Cile 2
GR - Grecia 2
JO - Giordania 2
KE - Kenya 2
KG - Kirghizistan 2
OM - Oman 2
PE - Perù 2
PY - Paraguay 2
RS - Serbia 2
SA - Arabia Saudita 2
SN - Senegal 2
AF - Afghanistan, Repubblica islamica di 1
AM - Armenia 1
BG - Bulgaria 1
BN - Brunei Darussalam 1
BO - Bolivia 1
BS - Bahamas 1
CO - Colombia 1
CR - Costa Rica 1
DM - Dominica 1
DO - Repubblica Dominicana 1
ET - Etiopia 1
GN - Guinea 1
GY - Guiana 1
HN - Honduras 1
HU - Ungheria 1
JM - Giamaica 1
KW - Kuwait 1
LU - Lussemburgo 1
MD - Moldavia 1
NG - Nigeria 1
NI - Nicaragua 1
NO - Norvegia 1
NP - Nepal 1
PH - Filippine 1
QA - Qatar 1
RO - Romania 1
SK - Slovacchia (Repubblica Slovacca) 1
SR - Suriname 1
TH - Thailandia 1
TT - Trinidad e Tobago 1
TZ - Tanzania 1
XK - ???statistics.table.value.countryCode.XK??? 1
Totale 9.156
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Città #
Chandler 649
Jacksonville 647
Dublin 609
Singapore 571
Dallas 406
Hong Kong 249
Boardman 219
Santa Clara 208
Ashburn 206
Izmir 134
New York 133
Nanjing 121
Wilmington 115
Beijing 108
San Mateo 99
Munich 86
Lawrence 85
Princeton 85
Moscow 56
Ann Arbor 54
Dearborn 53
The Dalles 49
Los Angeles 48
Nanchang 48
L'aquila 46
Milan 45
Shenyang 37
Turku 33
São Paulo 31
Brno 30
Seattle 29
Hefei 27
Verona 26
Helsinki 25
Ho Chi Minh City 25
Mountain View 25
Tianjin 25
Des Moines 22
Dong Ket 22
Brussels 20
Council Bluffs 20
Falls Church 20
Columbus 19
Warsaw 19
Rome 18
Shanghai 18
Bremen 17
Frankfurt am Main 17
Hebei 17
Tokyo 17
Denver 15
L’Aquila 15
Philadelphia 15
Woodbridge 15
Boston 13
Impruneta 13
Montreal 13
Orem 13
Brooklyn 12
Guangzhou 12
Nuremberg 12
Chennai 11
Jinan 11
Johannesburg 11
Kunming 11
Stockholm 11
Falkenstein 10
Jiaxing 10
London 10
Rio de Janeiro 10
Norwalk 9
Phoenix 9
Poplar 9
Vienna 9
Washington 9
Ningbo 8
Pescara 8
San Francisco 8
Taizhou 8
Zhengzhou 8
Ankara 7
Atlanta 7
Brasília 7
Changsha 7
Curitiba 7
Houston 7
Mexico City 7
Salvador 7
Toronto 7
Auburn Hills 6
Changchun 6
Düsseldorf 6
Hangzhou 6
Kitzingen 6
Manchester 6
Montevideo 6
Recife 6
West Jordan 6
Amsterdam 5
Campinas 5
Totale 6.143
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Nome #
TRAIL induces pro-apoptotic crosstalk between the TRAIL-receptor signaling pathway and TRKIII in SH-SY5Y cells, unveiling a potential therapeutic “Achilles heel” for the TrkAIII oncoprotein in neuroblastoma 160
Constitutive autotaxin transcription by Nmyc-amplified and non-amplified neuroblastoma cells is regulated by a novel AP-1 and SP-mediated mechanism and abrogated by curcumin 155
NGF sensitizes TrkA SH-SY5Y neuroblastoma cells to TRAIL-induced apoptosis 151
TrkAIII signals endoplasmic reticulum stress to the mitochondria in neuroblastoma cells, resulting in glycolytic metabolic adaptation 140
TrkA alternative splicing: A regulated tumor-promoting switch in human neuroblastoma 137
Real-life multidisciplinary treatment for unresectable colorectal cancer liver metastases including hepatic artery infusion with chemo-filtration and liquid biopsy precision oncotherapy: observational cohort study 137
Gelatinase B/MMP-9 in Tumour Pathogenesis and Progression. 128
The neuroblastoma tumour-suppressor TrkAI and its oncogenic alternative TrkAIII splice variant exhibit geldanamycin-sensitive interactions with Hsp90 in human neuroblastoma cells 127
Transcriptional regulation of intercellular adhesion molecule 1 by phorbol ester in human neuroblastoma cell line SK-N-SH involves jun- and fos-containing activator protein 1 site binding complex(es) 126
Multidisciplinary Treatment, Including Locoregional Chemotherapy, for Merkel-Polyomavirus-Positive Merkel Cell Carcinomas: Perspectives for Patients Exhibiting Oncogenic Alternative Δ exon 6–7 TrkAIII Splicing of Neurotrophin Receptor Tropomyosin-Related Kinase A 123
Circulating tumour cell gene expression and chemosensitivity analyses: predictive accuracy for response to multidisciplinary treatment of patients with unresectable refractory recurrent rectal cancer or unresectable refractory colorectal cancer liver metastases 119
Transcriptional up-regulation of matrix metalloproteinase-9 expression during spontaneous epithelial to neuroblast phenotype conversion by SK-N-SH neuroblastoma cells, involved in enhanced invasivity, depends upon GT-box and nuclear factor kappa B elements 119
A pilot study of alternative TrkAIII splicing in Merkel cell carcinoma: a potential oncogenic mechanism and novel therapeutic target 119
The enemy from within: Miss-localization of a compromised receptor as a mechanism for TrkAIII oncogenic activity 118
Thioredoxin alters the matrix metalloproteinase/tissue inhibitors of metalloproteinase balance and stimulates human SK-N-SH neuroblastoma cell invasion 117
Precision oncotherapy based on liquid biopsies in multidisciplinary treatment of unresectable recurrent rectal cancer: a retrospective cohort study 115
Alendronate promotes plasmin-mediated MMP-9 inactivation by exposing cryptic plasmin degradation sites within the MMP-9 catalytic domain. 115
All-trans-retinoic acid induces nuclear factor kappa B activation and matrix metalloproteinase-9 expression and enhances basement membrane invasivity of differentiation-resistant human SK-N-BE 9N neuroblastoma cells 114
TRAIL induces pro-apoptotic crosstalk between the TRAIL-receptor signaling pathway and TrkAIII in SH-SY5Y cells 114
TrkAIII promotes microtubule nucleation and assembly at the centrosome in SH-SY5Y neuroblastoma cells, contributing to an undifferentiated anaplastic phenotype. 113
Inhibition of human MDA-MB-231 breast cancer cell invasion by matrix metalloproteinase 3 involves degradation of plasminogen 113
The oncogenic neurotrophin receptor tropomyosin-related kinase variant, TrkAIII 111
Hypoxia-induced alternative splicing: the 11th Hallmark of Cancer 110
EGF- and cell-cycle-regulated STAG1/PMEPA1 ERG1.2 belongs to a conserved gene family and is overexpressed and amplified in breast and ovarian cancer 109
NGF FLIPs TrkA onto the death TRAIL in neuroblastoma cells 109
The Alternative TrkAIII Splice Variant, a Targetable Oncogenic Participant in Human Cutaneous Malignant Melanoma 108
Alternative TrkAIII splicing: a potential regulated tumor-promoting switch and therapeutic target in Neuroblastoma 108
Retrograde TrkAIII transport from ERGIC to ER: a re-localisation mechanism for oncogenic activity 108
Neurotrophin and Neurotrophin Receptor Involvement in Human Neuroblastoma 108
Multidisciplinary palliation for unresectable recurrent rectal cancer: Hypoxic pelvic perfusion with mitomycin C and oxaliplatin in patients progressing after systemic chemotherapy and radiotherapy, a retrospective cohort study 107
A Prospective Study of Intraarterial Infusion Chemotherapy in Advanced WT BRAF Melanoma Patients 107
Successful laparoscopic trans-peritoneal repair of an incisional inguinal hernia, resulting from deep lymph node dissection for melanoma: A case report 106
A Pilot Study of the Predictive Potential of Chemosensitivity and Gene Expression Assays Using Circulating Tumour Cells from Patients with Recurrent Ovarian Cancer 102
Pyrrolopyrimidine c-Src inhibitors reduce growth, adhesion, motility and invasion of prostate cancer cells in vitro 101
Cis Golgi network-associated TrkAIII targets the interphase centrosome and promotes genetic instability 100
Activation of MMP-2 by human GCT23 giant cell tumour cells induced by osteopontin, bone sialoprotein and GRGDSP peptides is RGD and cell shape change dependent 99
TrkAIII expression in the thymus 99
Discovery, characterization and potential roles of a novel NF-YAx splice variant in human neuroblastoma 98
Doxorubicin-Induced TrkAIII Activation: A Selection Mechanism for Resistant Dormant Neuroblastoma Cells 98
A TaqMan-Based qRT-PCR Assay for Accurate Evaluation of the Oncogenic TrkAIII Splice Variant in Tumor cDNAs 95
Tyrosine kinase Src inhibitors: Cellular mechanisms for potential therapeutic applications in bone disease. 95
TRKAIII COMMUNICATES ER-STRESS TO THE MITO-CHONDRIA IN NEUROBLASTOMA CELLS, RESULTING INGLYCOLYTIC METABOLIC ADAPTATION 95
FOLLICLE-STIMULATING HORMONE INCREASES THE EXPRESSION OF TISSUE INHIBITORS OF METALLOPROTEINASES TIMP-1 AND TIMP-2 AND INDUCES TIMP-1 AP-1 SITE BINDING COMPLEX(ES) IN PREPUBERTAL RAT SERTOLI CELLS 94
Increased chemiluminescence of polymorphonuclear leucocytes from patients with progressive systemic sclerosis 94
The interaction of leucocytes with vascular endothelial cells in vitro with respect to experimental inflammation in the rat 94
Alternative TrkA splicing and neuroblastoma 93
Circulating tumour cell liquid biopsy in selecting therapy for recurrent cutaneous melanoma with locoregional pelvic metastases: A pilot study 93
Effect of phorbol ester and cytokines on matrix metalloproteinase and tissue inhibitor of metalloproteinase expression in tumor and normal cell lines. 92
DIFFERENTIAL EXPRESSION OF TUMOR-CELL METALLOPROTEINASES AND TIMPS BY A PHORBOL ESTER 92
Mode of formation of synovial villi 92
The effect of GRGDSP peptide, osteopontin and bone sialoprotein on metalloproteinases, tissue inhibitors of metalloproteinases, and plasminogen activators secreted by human osteoclastoma cells. 91
Nifedipine in the treatment of Raynaud's phenomenon in patients with systemic sclerosis 91
The TrkAIII oncoprotein inhibits mitochondrial free radical ROS-induced death of SH-SY5Y neuroblastoma cells by augmenting SOD2 expression and activity at the mitochondria, within the context of a tumour stem cell-like phenotype. 91
MAPPING OF RECEPTOR-BINDING SITES ON IL-1-BETA BY RECONSTRUCTION OF IL-1RA-LIKE DOMAINS 90
TrkAIII: A Novel Hypoxia-regulated Alternative TrkA Splice Variant of Potential Physiological and Pathological Importance 90
Mechanisms involved in selecting and maintaining neuroblastoma cancer stem cell populations, and perspectives for therapeutic targeting 89
REN: a novel, developmentally regulated gene that promotes neural cell differentiation 89
RAS LEVELS AND METALLOPROTEINASE ACTIVITY IN NORMAL VERSUS NEOPLASTIC RAT MAMMARY TISSUES 88
Thioredoxin stimulates MMP-9 expression, de-regulates the MMP-9/TIMP-1 equilibrium and promotes MMP-9 dependent invasion in human MDA-MB-231 breast cancer cells. 88
IDENTIFICATION OF THE 72-KDA (MMP-2) AND 92-KDA (MMP-9) GELATINASE TYPE-IV COLLAGENASE IN PREPARATIONS OF LAMININ AND MATRIGEL(TM) 87
Thioredoxin inhibits microvascular endothelial capillary tubule formation 87
Immune response activation following hyperthermic intraperitoneal chemotherapy for peritoneal metastases: A pilot study 87
Identification of plasminogen in Matrigel(TM) and its activation by reconstitution of this basement membrane extract 86
BASEMENT-MEMBRANE TYPE-IV COLLAGEN DEGRADATION - EVIDENCE FOR THE INVOLVEMENT OF A PROTEOLYTIC CASCADE INDEPENDENT OF METALLOPROTEINASES 85
Reconstitution of TIMP-2 expression in SH-SY5Y neuroblastoma cells by 5-azacytidine is mediated transcriptionally by NF-Y through an inverted CCAAT site 85
RETINOIC ACID-ENHANCED INVASION THROUGH RECONSTITUTED BASEMENT MEMBRANE BY HUMAN SK-N-SH NEUROBLASTOMA CELLS INVOLVES MEMBRANE-ASSACIATED TISSUE-TYPE PLASMINOGEN ACTIVATOR 85
STUDIES ON THE EFFECTS OF LAMININ, E-8 FRAGMENT OF LAMININ AND SYNTHETIC LAMININ PEPTIDES PA22-2 AND YIGSR ON MATRIX METALLOPROTEINASES AND TISSUE INHIBITOR OF METALLOPROTEINASE EXPRESSION 85
Advanced Merkel cell carcinoma of the lower extremity treated with surgery and isolated pelvic and limb perfusion using Melphalan: A case of unexpected long-term survival 85
Opposing roles for specific TIMPs in breast cancer prognostic 84
Alternative TrkAIII splicing and Cancer 84
Alternative TrkA splicing and Cancer 83
bcl-2 over-expression enhances NF-κB activity and induces mmp-9 transcription in human MCF7(ADR) breast-cancer cells 83
Effect of a lymphocyte-derived pro-inflammatory factor on carrageenan pleurisy in the rat 83
The transition from acute to chronic inflammation 83
The alternative TRKAIII splice variant targets the centrosome and promotes genetic instability 80
Studies into the mode of action of non-steroidal anti-inflammatory drugs using a model of facsimile synovium 80
A Study of Alternative TrkA Splicing Identifies TrkAIII as a Novel Potentially Targetable Participant in PitNET Progression 80
Tissue inhibitor of metalloproteinase-2 protection of matrix metalloproteinase-2 from degradation by plasmin is reversed by divalent cation chelator EDTA and the bisphosphonate alendronate 79
NGF Sensitizes TrkA SH-SY5Y Neuroblastoma Cells to TRAIL-Induced Apoptosis 77
EXPRESSION OF 72 KD GELATINASE AND TYPE-IV COLLAGEN DURING CARBON TETRACHLORIDE-INDUCED RAT-LIVER FIBROSIS 76
Characterisation of metastatic tumour cells 74
Spontaneous metastasis of rat liver epithelial cells transformed with v-raf and v-raf/v-myc: association with different phenotypic properties 72
Enhancement of colloidal clearance in normal rats by sodium diethyl dithiocarbamate (DTC) 72
STUDIES ON THE ABILITY OF 65-KDA AND 92-KDA TUMOR-CELL GELATINASES TO DEGRADE TYPE-IV COLLAGEN 72
Molecular Characterization and Inhibition of a Novel Stress-Induced Mitochondrial Protecting Role for Misfolded TrkAIII in Human SH-SY5Y Neuroblastoma Cells 71
The effects of levan on the acute inflammatory response 71
Pyrrolopyrimidine class Src inhibitors inhibit osteoclast and bone metastatic tumor cell functions. 67
Nutraceutical Preventative and Therapeutic Potential in Neuroblastoma: From Pregnancy to Early Childhood 66
The alternative TrkAIII splice variant expressed by human neuroblastomas and glioblastomas targets the centrosome and promotes genetic instability 66
Isolation and characterization of human natural killer cells 65
The role of plasma factors in the adherence of leucocytes to vascular endothelial cells 63
Effect of acute acupuncture on acute inflammation 62
NGF sensitizes TrKA expressing SH-SY5Y nuroblastoma cells to TRAIL-induced apoptosisi 62
The TrkAIII splice variant oncoprotein enhances PD-L1 expression in human SH-SY5Y neuroblastoma cells 61
A TAQMAN-BASED QRT-PCR ASSAY FOR DETECTING TRKAIII EXPRESSION IN TUMOR TISSUE RNAS 60
Studies on potentially druggable pathways that regulate stress-induced TrkAIII mitochondrial internalization, cleavage and activation in human neuroblastoma cells 58
Hypoxia-induced alternative TrkA splicing and reoxygenation-dependent TrkAIII activation: A cycling hypoxia-regulated resistance mechanism in neuroblastoma. 57
TRKAIII PROMOTES PD-L1 EXPRESSION IN SH-SY5Y NEUROBLASTOMA CELLS 42
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Totale 9.333
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Categoria #
all - tutte 41.379
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 41.379
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021411 0 0 0 0 0 16 92 10 88 20 147 38
2021/2022503 35 41 59 23 40 13 13 34 28 11 40 166
2022/20231.790 125 113 39 190 169 205 3 99 764 10 40 33
2023/2024472 60 24 44 46 33 137 1 22 5 13 8 79
2024/20252.028 50 34 165 101 237 168 293 174 348 139 169 150
2025/20261.935 174 354 314 531 416 146 0 0 0 0 0 0
Totale 9.333